國家衛生研究院 NHRI:Item 3990099045/15870
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    题名: Chlorine-containing polyacetoxybriarane diterpenoids from the octocoral Junceella fragilis
    作者: Do, HN;Chen, YT;Chien, SY;Chen, YY;Zhang, MM;Tsou, LK;Chen, JJ;Wen, ZH;Lo, YH;Zheng, LG;Sung, PJ
    贡献者: Institute of Molecular and Genomic Medicine;Institute of Biotechnology and Pharmaceutical Research
    摘要: The chemical screening of an octocoral identifed as Junceella fragilis has led to the isolation of five chlorinated briarane-type diterpenoids, including three known metabolites, gemmacolide X (1), frajunolide I (2), and fragilide F (3), along with two new analogs, 12α-acetoxyfragilide F (4) and 12α-acetoxyjunceellin (5). Single-crystal X-ray diffraction analysis was carried out to determine the absolute configurations of 1 and 2, while the structures of new compounds 4 and 5 were ascertained with 2D NMR experiments. Briaranes 1 and 3-5 were active in enhancing alkaline phosphatase (ALP) activity.
    日期: 2024-05-28
    關聯: RSC Advances. 2024 May 28;14:17195-17201.
    Link to: http://dx.doi.org/10.1039/d4ra03062a
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2046-2069&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:001234790400001
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=85194499933
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