國家衛生研究院 NHRI:Item 3990099045/16649
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    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/16649


    题名: Heterocyclic compounds and their application
    作者: Shih, C;Shia, KS;Wu, CH;Choi, Ming Chen;Song, JS;Wang, Y
    贡献者: Institute of Biotechnology and Pharmaceutical Research;Center for Neuropsychiatric Research
    摘要: FIELD: medicine; pharmaceutics.SUBSTANCE: invention relates to heterocyclic compounds of the formula (I), where R1and R2are independently H, NH2or C1-6alkyl, or R1and R2, together with two carbon atoms with which they are bound, are phenyl or heteroaryl selected from thienyl, imidazolyl and pyridyl; each of R3and R4is independently, or, which are such as disclosed in the claims; R5is H; R6is absent or is H; R7is C3-10cycloalkyl. The invention also relates to a pharmaceutical composition containing a compound of the formula (I), to a method for mobilizing hematopoietic stem cells (HSC) and endothelial progenitor cells (EPC) into peripheral blood circulation and to a method for treating hepatocellular carcinoma, renal damage, myocardial infarction, or mild traumatic brain injury.EFFECT: technical result is compounds of the formula (I) used to disrupt the interaction between CXCR4 and CXCL12.(I)31 cl, 8 ex
    日期: 2021-09-24
    關聯: RU2756055/2021-09-24
    Link to: https://tiponet.tipo.gov.tw/gpss2/gpsskmc/gpssbkm?!!FRURLRU2756055C2
    显示于类别:[夏克山] 專利
    [石全(2014-2017)] 專利
    [王昀] 專利

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