國家衛生研究院 NHRI:Item 3990099045/1784
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/1784


    Title: Tests for equivalence based on odds ratio for matched-pair design
    Authors: Liu, JP;Fan, HY;Ma, MC
    Contributors: Division of Biostatistics and Bioinformatics
    Abstract: Currently, methods for evaluation of equivalence under a matched-pair design use either difference in proportions or relative risk as measures of risk association. However, these measures of association are only for cross-sectional studies or prospective investigations, such as clinical trials and they cannot be applied to retrospective research such as case-control studies. As a result, under a matched-pair design, we propose the use of the conditional odds ratio for assessment of equivalence in both prospective and retrospective research. We suggest the use of the asymptotic confidence interval of the conditional odds ratio for evaluation of equivalence. In addition, a score test based on the restricted maximum likelihood estimator (RMLE) is derived to test the hypothesis of equivalence under a matched-pair design. On the other hand, a sample size formula is also provided. A simulation study was conducted to empirically investigate the size and power of the proposed procedures. Simulation results show that the score test not only adequately controls the Type I error but it can also provide suffcient power. A numerical example illustrates the proposed methods.
    Keywords: Pharmacology & Pharmacy;Statistics & Probability
    Date: 2005
    Relation: Journal of Biopharmaceutical Statistics. 2005;15(6):889-901.
    Link to: http://dx.doi.org/10.1080/10543400500265561
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1054-3406&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000236233300001
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=27544479042
    Appears in Collections:[Jen-Pei Liu(1998-2002)] Periodical Articles

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