國家衛生研究院 NHRI:Item 3990099045/1824
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    題名: Impact of chronic hepatitis B virus (HBV) infection on outcomes of patients infected with HIV in an area where HBV infection is hyperendemic
    作者: Sheng, WH;Chen, MY;Hsieh, SM;Hsiao, CF;Wang, JT;Hung, CC;Chang, SC
    貢獻者: Division of Biostatistics and Bioinformatics
    摘要: Between June 1994 and February 2003, a total of 111 human immunodeficiency virus (HIV)-infected patients with chronic hepatitis B virus (HBV) coinfection and 387 HIV-infected patients without HBV or hepatitis C virus coinfection were prospectively observed to assess the impact of HBV infection on outcomes of HIV-infected patients. After a median duration of observation of 25 months, coinfected patients were more likely to develop hepatitis ( adjusted hazard ratio [AHR], 2.54; 95% confidence interval [CI], 1.69 - 3.82) and hepatic decompensation ( adjusted odds ratio [AOR], 9.94; 95% CI, 1.89 - 52.35). Although similar proportions of the 2 patient groups had an increase in the CD4 count by greater than or equal to100 x 10(6) cells/L (AOR, 0.78; 95% CI, 0.45 - 1.36) and development of new opportunistic illnesses (AOR, 0.94; 95% CI, 0.53 - 1.66), HBV-infected patients had an increased risk for virologic failure (AOR, 1.76; 95% CI, 1.03 - 2.99) and death ( AHR, 1.71; 95% CI, 1.19 - 2.47) after highly active antiretroviral therapy was initiated.
    關鍵詞: Immunology;Industrial Relations & Labor;Infectious Diseases;Microbiology
    日期: 2004-05-15
    關聯: Clinical Infectious Diseases. 2004 May;38(10):1471-1477.
    Link to: http://dx.doi.org/10.1086/420744
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1058-4838&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000221173300022
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=2442638839
    顯示於類別:[蕭金福] 會議論文/會議摘要

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