國家衛生研究院 NHRI:Item 3990099045/1913
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    題名: Antibiotic usage in community-acquired infections in hospitals in Taiwan
    作者: Ho, M;Chang, FY;Yin, HC;Ben, RJ;Chang, LY;Chen, PY;Cheng, SH;Chen, ST;Huang, FL;Lin, HC;Lu, DCT;Wang, NC;Wang, JT
    貢獻者: Division of Clinical Research
    摘要: Background and Purpose: Using an epidemiologically meaningful in-hospital population with community-acquired infections, we evaluated antibiotic therapy In terms of indication and choice of antibiotic and microbiologic work-up. Methods:. Infectious disease specialists evaluated charts of 436 patients from 9 hospitals and selected those who received antibiotics within 3 days of admission, Each antibiotic prescribed was marked for appropriateness, of indication and choice. Microbiologic isolates were evaluated for their clinical significance. Results: The most common infections were in the lower respiratory tract (46.1%). Each patient received a mean of 2.25 antibiotics for 8.1 +/- 6.4 days. Of the 975 courses Of antibiotics given in the study period. indication and choice were correct in 37.4% and unsatisfactory in 14.5%. The vast majority Of antibiotics used (79.2%) were first-line antibiotics - usually first-generation cephalosporins aminoglycosides, and aminopenicillins. Most patients (66%) had a microbiology, laboratory work-Up, but Only 37.4Y were judged by evaluators to have a meaningful microbiologic diagnosis. Among the 201 patients With lower respiratory tract infections, 105 (52.2%) had a diagnosis Of pneumonia. A positive isolate was recovered in 30 (28.6%) patients, and most of these isolates (20.68.7%) were aerobic gram-negative rods. There were three positive blood cultures but none grew Streptococcus pneumoniae Conclusions: Antibiotics, were used excessively in number and duration. The microbiologic work-Up had little effect on the indication and choice of antibiotics. Community-acquired pneumoniae differed markedly, from that in Western countries in that only 3.3% were caused by S. pneumoniae.
    關鍵詞: Medicine, General & Internal
    日期: 2002-01
    關聯: Journal of the Formosan Medical Association. 2002 Jan;101(1):34-42.
    Link to: http://www.fma.org.tw/fagmag/pdfiles/101_1/101-1-34.pdf
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0929-6646&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000174509700005
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0036123486
    顯示於類別:[何曼德(1997-2002)] 期刊論文

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