| 2008-08 |
Transcriptional repression of O-6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N '-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells |
Molecular Pharmacology. 2008 Aug;74(2):517-526. |
 |
| 2008-07-24 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors |
Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355. |
|
| 2008-02 |
A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells |
Anti-Cancer Drugs. 2008 Feb;19(2):151-158. |
|
| 2007-11-15 |
Tamoxifen accelerates proteasomal degradation of O-6-methylguanine DNA methyltransferase in human cancer cells |
International Journal of Cancer. 2007 Nov;121(10):2293-2300. |
|
| 2007-10 |
A novel oral indoline-sulfonamide agent, N-[1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-Isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule |
Journal of Pharmacology and Experimental Therapeutics. 2007 Oct;323(1):398-405. |
|
| 2007-09-06 |
4-and 5-aroylindoles as novel classes of potent antitubulin agents |
Journal of Medicinal Chemistry. 2007 Sep;50(18):4548-4552. |
|
| 2007-07-31 |
Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil |
British Journal of Cancer. 2007 Jul;97(3):334-344. |
|
| 2007-02-26 |
Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana |
Tetrahedron Letters. 2007 Feb;48(9):1567-1569. |
|
| 2007-01 |
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation |
Molecular Cancer Therapeutics. 2007 Jan;6(1):193-202. |
|
| 2006-11-27 |
C-35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines |
Journal of Natural Products. 2006 Nov;69(11):1611-1613. |
|
| 2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents |
Journal of Medicinal Chemistry. 2006 Nov;49(23):6656-6659. |
|
| 2006-11 |
Combined modalities of resistance in an oxaliplaitin-resistant human gastric cancer cell line with enhanced sensitivity |
EJC Supplements. 2006 Nov;4(12):59. |
|
| 2006-11 |
D-501036, a novel selenophene-base triheterocycle derivative exhibits potent in vitro and in vivo anti-tumoral activity, which involves DNA-damage and ATM activation |
EJC Supplements. 2006 Nov;4(12):92. |
|
| 2006-11 |
Tamoxifen induces degradation of the o6-methylguanine DNA methyltransferase protein via the ubiquitin-dependent proteosome pathway in human cancer cells |
EJC Supplements. 2006 Nov;4(12):155. |
|
| 2006-10-19 |
2-amino and 2 '-aminocombretastatin derivatives as potent antimitotic agents |
Journal of Medicinal Chemistry. 2006 Oct;49(21):6412-6415. |
|
| 2006-10 |
Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents |
ChemMedChem. 2006 Oct;1(10):1106-1118. |
|
| 2006-02 |
DNA repair enzyme, O-6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors |
Journal of Pharmacology and Experimental Therapeutics. 2006 Feb;316(2):946-954. |
|
| 2005-02 |
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa |
Phytochemistry. 2005 Feb;66(4):495-501. |
|
| 2005-01 |
Four new 6-Nor-5(6 →7)abeo-abietane type diterpenes and antitumoral cytotoxic diterpene constituents from the bark of Taiwania cryptomerioides |
Planta Medica. 2005 Jan;71(1):72-76. |
|
| 2004-09 |
Drug design of BPR0L075 as an anticancer agent |
World Conference on Magic Bullets - Celebrating Paul Ehrlich's 150th Birthday. 2004 Sep 9-11:Abstract # 203. |
|
| 2004-07-15 |
A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells |
Biochemical Pharmacology. 2004 Jul;68(2):293-303. |
|
| 2004-07-01 |
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo |
Cancer Research. 2004 Jul;64(13):4621-4628. |
|
| 2004-07 |
Drug design for BPR0L075 as an anticancer agent |
Medicine in the 21st Century Tri-Conference & Bio-Forum 2004 Shanghai International Convention Center. 2004 Jul. |
|
| 2004-01-01 |
Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells |
Molecular Pharmacology. 2004 Jan;65(1):77-84. |
|
| 2004-01 |
Three new oleanane-type triterpenes from Ludwigia octovalvis with cytotoxic activity against two human cancer cell lines |
Journal of Natural Products. 2004 Jan;67(1):91-93. |
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