國家衛生研究院 NHRI:Item 3990099045/2050
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    题名: Multilocus sequence typing of Candida tropicalis shows clonal cluster enriched in isolates with resistance or trailing growth of fluconazole
    作者: Chou, HH;Lo, HJ;Chen, KW;Liao, MH;Li, SY
    贡献者: Division of Clinical Research
    摘要: Multilocus sequence typing (MLST) was used to characterize the genetic profiles of 52 Candida tropicalis isolates collected from 10 hospitals in Taiwan. A total of 33 diploid sequence types (DSTs) were differentiated among the 52 isolates and all were novel to the Internet C. tropicalis DST database (http://pubmlst.org/ctropicalis/). Eleven (33.3%) of the 33 DSTs could be assigned to 3 major clonal clusters (1-3) based on eBURST calculation. Only clonal cluster I co-clustered isolates from UK and the United States. Clonal cluster 2 was enriched with isolates with resistance or trailing growth of fluconazole (14/20, 70%). Furthermore, there are a number of pulsed-field gel electrophoresis subtypes associated with the isolates in this cluster, demonstrating that possibly more than one clone with resistant or trailing property have emerged and spread in Taiwan in 1999. (c) 2007 Elsevier Inc. All rights reserved.
    关键词: Infectious Diseases;Microbiology
    日期: 2007-08
    關聯: Diagnostic Microbiology and Infectious Disease. 2007 Aug;58(4):427-433.
    Link to: http://dx.doi.org/10.1016/j.diagmicrobio.2007.03.014
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0732-8893&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000248937500008
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=34547556097
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