國家衛生研究院 NHRI:Item 3990099045/2068
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    题名: In vitro activity of voriconazole against Candida species isolated in Taiwan
    作者: Yang, YL;Cheng, HH;Lo, HJ
    贡献者: Division of Clinical Research
    摘要: The activity of voriconazole was determined against 285 Candida species consisting of 53 resistant isolates, 43 susceptible-dose dependent and 189 isolates susceptible to fluconazole. The MIC50 and MIC90 to fluconazole were 8 and 64 mg/l, respectively. The range of minimum inhibitory concentrations (MICs) to voriconazole was from 0.0325 to 2 mg/l and the MIC50 and MIC90 were 0.125 and 0.5 mgA, respectively. Only 3 of 285 tested isolates had MICs to voriconazole equal to 2 mg/l. A total of 38 isolates, consisted of 3 Candida albicans, 5 Candida krusei, 7 Candida tropicalis and 21 Candida glabrata, had MICs greater than or equal to 0.5 mg/l to voriconazole. There was correlation between the susceptibility to fluconazole and voriconazole. (C) 2004 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.
    关键词: Infectious Diseases;Microbiology;Pharmacology & Pharmacy
    日期: 2004-09
    關聯: International Journal of Antimicrobial Agents. 2004 Sep;24(3):294-296.
    Link to: http://dx.doi.org/10.1016/j.ijantimicag.2004.01.014
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0924-8579&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000224070400016
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=4344638941
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