國家衛生研究院 NHRI:Item 3990099045/2071
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    题名: Distribution and susceptibility to amphotericin B and fluconazole of Candida spp. isolated from Taiwan
    作者: Yang, YL;Ho, YA;Cheng, HH;Lo, HJ
    贡献者: Division of Clinical Research
    摘要: Susceptibilities to amphotericin B and fluconazole of 628 clinical yeast strains collected from 22 hospitals in Taiwan were determined. A total of 53 isolates (8.4%) were resistant to fluconazole. Each hospital had different resistance rate to fluconazole ranging from 0 % to 24 %. None of the 186 isolates from eight of the 22 hospitals was resistant to fluconazole. In contrast, isolates from nine of the remaining 14 hospitals had greater than 10 % resistance rate to fluconazole. Consistently, 88.9 % (8/9) fluconazole-resistant C. albicans isolates were from hospitals having a high resistance rate to fluconazole. The prevalence of various Candida spp. in each hospital was different. A positive association was found between the prevalence of C. tropicalis and the resistance rate to fluconazole for individual hospitals. Although only three isolates (0.5 %) were resistant to amphotericin B, a co-resistance to both amphotericin B and fluconazole was observed, which highlights the emerging problem of drug resistance.
    关键词: Public, Environmental & Occupational Health;Infectious Diseases
    日期: 2005-04
    關聯: Epidemiology and Infection. 2005 Apr;133(2):325-330.
    Link to: http://dx.doi.org/10.1017/S0950268804003310
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0950-2688&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000228028300015
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=15944399740
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