| 2009-12-01 |
芳香羰吲哚化合物 |
I317634/2009-12-01 |
|
| 2009-12 |
Alpha-fetoprotein response in advanced hepatocellular carcinoma receiving cytostatic agent |
Journal of Clinical Oncology. 2009 Dec;27(36):e271. |
 |
| 2009-09 |
Synergistic augmentation of arsenic trioxide-induced cytotoxicity by BCNU through reactive oxygen species-related autophagic pathway in human solid tumors |
EJC Supplements. 2009 Sep;7(3):16. |
|
| 2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945. |
|
| 2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity |
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233. |
|
| 2009-07-03 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers |
Molecular Cancer. 2009 Jul 3;8:Article number 43. |
|
| 2009-05-20 |
Randomized, phase I, and pharmacokinetic (PK) study of RAD001, an mTOR inhibitor, in patients (pts) with advanced hepatocellular carcinoma (HCC) |
Journal of Clinical Oncology. 2009 May 20;27(15s):Abstract number 4587. |
|
| 2009-05-05 |
Indole compounds |
US7528165B2/2009-05-05 |
|
| 2009-05 |
Down-regulation of survivin enhances sensitivity to BPROL075 in human cancer cells via caspase-independent mechanisms |
Cancer Research. 2009 May;69:Abstract number 5542. |
|
| 2009-04-17 |
Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents |
ChemMedChem. 2009 Apr 17;4(4):588-593. |
|
| 2009-04 |
Aurora kinase inhibitors in preclinical and clinical testing |
Expert Opinion on Investigational Drugs. 2009 Apr;18(4):379-398. |
|
| 2009-04 |
Increasing incidence of intrahepatic cholangiocarcinoma and its relationship to chronic viral hepatitis |
Journal of the National Comprehensive Cancer Network. 2009 Apr;7(4):423-427. |
|
| 2009-03 |
Advances in Aurora kinase inhibitor patents |
Expert Opinion on Therapeutic Patents. 2009 Mar;19(3):321-356. |
|
| 2008-12-25 |
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents |
Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167. |
|
| 2008-11-25 |
Anti-tumor compounds |
US7456289B2/2008-11-25 |
|
| 2008-10-28 |
Human DNA polymerase eta activity and translocation is regulated by phosphorylation |
Proceedings of the National Academy of Sciences of the United States of America. 2008 Oct 28;105(43):16578-16583. |
|
| 2008-10 |
Modern staging and utility of PET imaging in esophageal cancer management |
Journal of the National Comprehensive Cancer Network. 2008 Oct;6(9):862-869. |
|
| 2008-08 |
Transcriptional repression of O-6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N '-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells |
Molecular Pharmacology. 2008 Aug;74(2):517-526. |
|
| 2008-07-24 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors |
Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355. |
|
| 2008-05-01 |
抗腫瘤化合物 |
I296195/2008-05-01 |
|
| 2008-02 |
A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells |
Anti-Cancer Drugs. 2008 Feb;19(2):151-158. |
|
| 2007-11-15 |
Tamoxifen accelerates proteasomal degradation of O-6-methylguanine DNA methyltransferase in human cancer cells |
International Journal of Cancer. 2007 Nov;121(10):2293-2300. |
|
| 2007-10 |
A novel oral indoline-sulfonamide agent, N-[1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-Isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule |
Journal of Pharmacology and Experimental Therapeutics. 2007 Oct;323(1):398-405. |
|
| 2007-10 |
Human tissue kallikreins as prognostic biomarkers and as potential targets for anticancer therapy |
Expert Opinion on Therapeutic Patents. 2007 Oct;17(10):1227-1240. |
|
| 2007-09-06 |
4-and 5-aroylindoles as novel classes of potent antitubulin agents |
Journal of Medicinal Chemistry. 2007 Sep;50(18):4548-4552. |
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