| 2007-07-31 |
Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil |
British Journal of Cancer. 2007 Jul;97(3):334-344. |
 |
| 2007-07 |
A novel oral indoline-sulfonamide derivative, J30, exhibits potent activity against human cancer cells both in in vitro and in vivo through disruption of microtubule |
Drugs of the Future. 2007 Jul;32(Suppl. A):35-36. |
|
| 2007-03-01 |
Mitochondria-mediated and p53-associated apoptosis induced in human cancer cells by a novel selenophene derivative, D-501036 |
Biochemical Pharmacology. 2007 Mar;73(5):610-619. |
|
| 2007-02-26 |
Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana |
Tetrahedron Letters. 2007 Feb;48(9):1567-1569. |
|
| 2007-02-17 |
Lysosomal cysteine proteinase cathepsin S as a potential target for anti-cancer therapy |
Journal of Cancer Molecules. 2007 Feb 17;3(1):5-14. |
|
| 2007-01 |
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation |
Molecular Cancer Therapeutics. 2007 Jan;6(1):193-202. |
|
| 2006-12 |
Statistical quality control process for traditional Chinese medicine |
Journal of Biopharmaceutical Statistics. 2006 Dec;16(6):861-874. |
|
| 2006-11-27 |
C-35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines |
Journal of Natural Products. 2006 Nov;69(11):1611-1613. |
|
| 2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents |
Journal of Medicinal Chemistry. 2006 Nov;49(23):6656-6659. |
|
| 2006-11 |
Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma |
Cancer Chemotherapy and Pharmacology. 2006 Nov;58(5):654-664. |
|
| 2006-11 |
Combined modalities of resistance in an oxaliplaitin-resistant human gastric cancer cell line with enhanced sensitivity |
EJC Supplements. 2006 Nov;4(12):59. |
|
| 2006-11 |
D-501036, a novel selenophene-base triheterocycle derivative exhibits potent in vitro and in vivo anti-tumoral activity, which involves DNA-damage and ATM activation |
EJC Supplements. 2006 Nov;4(12):92. |
|
| 2006-11 |
Tamoxifen induces degradation of the o6-methylguanine DNA methyltransferase protein via the ubiquitin-dependent proteosome pathway in human cancer cells |
EJC Supplements. 2006 Nov;4(12):155. |
|
| 2006-10-19 |
2-amino and 2 '-aminocombretastatin derivatives as potent antimitotic agents |
Journal of Medicinal Chemistry. 2006 Oct;49(21):6412-6415. |
|
| 2006-10 |
Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents |
ChemMedChem. 2006 Oct;1(10):1106-1118. |
|
| 2006-09-25 |
Synthesis of new camptothecin analogues with the E-lactone ring replaced by alpha,beta-cyclohexenone |
European Journal of Organic Chemistry. 2006 Sep(19):4490-4499. |
|
| 2006-07-28 |
In vitro and in vivo studies of a novel potential anticancer agent of isochaihulactone on human lung cancer A549 cells |
Biochemical Pharmacology. 2006 Jul;72(3):308-319. |
|
| 2006-05 |
Antitubulin agents for the treatment of cancer - a medicinal chemistry update |
Expert Opinion on Therapeutic Patents. 2006 May;16(5):647-691. |
|
| 2006-05 |
Phase I study of biweekly gemcitabine followed by oxaliplatin and simplified 48-h infusion of fluorouracil/leucovorin for advanced pancreatic cancer |
Journal of Gastroenterology and Hepatology. 2006 May;21(5):874-879. |
|
| 2006-03 |
Phase I-II trial of weekly gemcitabine plus high-dose 5-fluorouracil and leucovorin in advanced pancreatic cancer |
Journal of Gastroenterology and Hepatology. 2006 Mar;21(3):531-536. |
|
| 2006-02 |
DNA repair enzyme, O-6-methylguanine DNA methyltransferase, modulates cytotoxicity of camptothecin-derived topoisomerase I inhibitors |
Journal of Pharmacology and Experimental Therapeutics. 2006 Feb;316(2):946-954. |
|
| 2006-01 |
Phase II study of gemcitabine plus vinorelbine in the treatment of cisplatin-resistant nasopharyngeal carcinoma |
Head and Neck. 2006 Jan;28(1):74-80. |
|
| 2005-12-01 |
Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives |
Bioorganic and Medicinal Chemistry. 2005 Dec;13(23):6513-6520. |
|
| 2005-12 |
Pulmonary embolism after transcatheter arterial chemoembolization |
European Journal of Cancer Care. 2005 Dec;14(5):440-442. |
|
| 2005-12 |
Induction of cell death by a novel selenophene derivative, D-501036, in human cancer cell lines |
Clinical Cancer Research. 2005 Dec;11(24):9101S. |
|
| 2005-09 |
Long-term complete remission of metastatic gastric cancer after weekly docetaxel, 24 h infusion of high-dose 5-FU/leucovorin and cisplatin |
Journal of Gastroenterology and Hepatology. 2005 Sep;20(9):1470-1471. |
|
| 2005-08-23 |
Indole compounds |
US6933316B2/2005-08-23 |
|
| 2005-08-01 |
alpha-fetoprotein response predicts survival benefits of thalidomide in advanced hepatocellular carcinoma |
Alimentary Pharmacology and Therapeutics. 2005 Aug;22(3):217-226. |
|
| 2005-06 |
Hepatocellular carcinoma associated with acquired von Willebrand disease and extreme thrombocytosis |
Annals of Oncology. 2005 Jun;16(6):988-989. |
|
| 2005-03-01 |
一種用以抑制癌細胞之醫藥組合物 |
I228417/2005-03-01 |
|
| 2005-02 |
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa |
Phytochemistry. 2005 Feb;66(4):495-501. |
|
| 2005-01 |
Four new 6-Nor-5(6 →7)abeo-abietane type diterpenes and antitumoral cytotoxic diterpene constituents from the bark of Taiwania cryptomerioides |
Planta Medica. 2005 Jan;71(1):72-76. |
|
| 2004-09 |
Drug design of BPR0L075 as an anticancer agent |
World Conference on Magic Bullets - Celebrating Paul Ehrlich's 150th Birthday. 2004 Sep 9-11:Abstract # 203. |
|
| 2004-08-12 |
Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents |
Journal of Medicinal Chemistry. 2004 Aug;47(17):4247-4257. |
|
| 2004-08-02 |
Phase II study of weekly oxaliplatin and 24-h infusion of high-dose 5-fluorouracil and folinic acid in the treatment of advanced gastric cancer |
British Journal of Cancer. 2004 Aug;91(3):453-458. |
|
| 2004-07-15 |
A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells |
Biochemical Pharmacology. 2004 Jul;68(2):293-303. |
|
| 2004-07-01 |
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo |
Cancer Research. 2004 Jul;64(13):4621-4628. |
|
| 2004-07 |
Drug design for BPR0L075 as an anticancer agent |
Medicine in the 21st Century Tri-Conference & Bio-Forum 2004 Shanghai International Convention Center. 2004 Jul. |
|
| 2004-05-20 |
Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents |
Journal of Medicinal Chemistry. 2004 May;47(11):2897-2905. |
|
| 2004-01-01 |
Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells |
Molecular Pharmacology. 2004 Jan;65(1):77-84. |
|
| 2004-01 |
Three new oleanane-type triterpenes from Ludwigia octovalvis with cytotoxic activity against two human cancer cell lines |
Journal of Natural Products. 2004 Jan;67(1):91-93. |
|
| 2004 |
Hepatocellular carcinoma with intra-atrial tumor thrombi - A report of three cases responsive to thalidomide treatment and literature review |
Oncology. 2004;67(3-4):320-326. |
|
| 2003-11-17 |
New analogues of AHMA as potential antitumor agents: Synthesis and biological activity |
Bioorganic and Medicinal Chemistry. 2003 Nov;11(23):4959-4969. |
|
| 2003-06-15 |
Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent |
Biochemical Pharmacology. 2003 Jun;65(12):2009-2019. |
|
| 2003-03-10 |
Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents (vol 13, pg 101, 2003) |
Bioorganic and Medicinal Chemistry Letters. 2003 Mar;13(5):977-977. |
|
| 2003-01-06 |
Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents |
Bioorganic and Medicinal Chemistry Letters. 2003 Jan;13(1):101-105. |
|
| 2002-10-09 |
2,2 '-diphenyl-1-picrylhydrazyl radical-scavenging active components from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) hulls |
Journal of Agricultural and Food Chemistry. 2002 Oct;50(21):5850-5855. |
|
| 2002-09-26 |
Antitumor AHMA linked to DNA minor groove binding agents: Synthesis and biological evaluation |
Journal of Medicinal Chemistry. 2002 Sep;45(20):4485-4493. |
|
| 2002-07-01 |
Novel mutation of topoisomerase I in rendering cells resistant to camptothecin |
Cancer Research. 2002 Jul;62(13):3716-3721. |
|
| 2002-07 |
Non-surgical treatment for afferent loop syndrome in recurrent gastric cancer complicated by peritoneal carcinomatosis: percutaneous transhepatic duodenal drainage followed by 24-hour infusion of high-dose fluorouracil and leucovorin |
Annals of Oncology. 2002 Jul;13(7):1151-1155. |
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