國家衛生研究院 NHRI:
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    显示项目176-200 / 254. (共11页)
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    日期题名關聯
    2009-12-01 芳香羰吲哚化合物 I317634/2009-12-01
    2009-12 Alpha-fetoprotein response in advanced hepatocellular carcinoma receiving cytostatic agent Journal of Clinical Oncology. 2009 Dec;27(36):e271.
    2009-09 Synergistic augmentation of arsenic trioxide-induced cytotoxicity by BCNU through reactive oxygen species-related autophagic pathway in human solid tumors EJC Supplements. 2009 Sep;7(3):16.
    2009-08-13 Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945.
    2009-07-23 Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233.
    2009-07-03 Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers Molecular Cancer. 2009 Jul 3;8:Article number 43.
    2009-05-20 Randomized, phase I, and pharmacokinetic (PK) study of RAD001, an mTOR inhibitor, in patients (pts) with advanced hepatocellular carcinoma (HCC) Journal of Clinical Oncology. 2009 May 20;27(15s):Abstract number 4587.
    2009-05-05 Indole compounds US7528165B2/2009-05-05
    2009-05 Down-regulation of survivin enhances sensitivity to BPROL075 in human cancer cells via caspase-independent mechanisms Cancer Research. 2009 May;69:Abstract number 5542.
    2009-04-17 Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents ChemMedChem. 2009 Apr 17;4(4):588-593.
    2009-04 Aurora kinase inhibitors in preclinical and clinical testing Expert Opinion on Investigational Drugs. 2009 Apr;18(4):379-398.
    2009-04 Increasing incidence of intrahepatic cholangiocarcinoma and its relationship to chronic viral hepatitis Journal of the National Comprehensive Cancer Network. 2009 Apr;7(4):423-427.
    2009-03 Advances in Aurora kinase inhibitor patents Expert Opinion on Therapeutic Patents. 2009 Mar;19(3):321-356.
    2008-12-25 Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167.
    2008-11-25 Anti-tumor compounds US7456289B2/2008-11-25
    2008-10-28 Human DNA polymerase eta activity and translocation is regulated by phosphorylation Proceedings of the National Academy of Sciences of the United States of America. 2008 Oct 28;105(43):16578-16583.
    2008-10 Modern staging and utility of PET imaging in esophageal cancer management Journal of the National Comprehensive Cancer Network. 2008 Oct;6(9):862-869.
    2008-08 Transcriptional repression of O-6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N '-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells Molecular Pharmacology. 2008 Aug;74(2):517-526.
    2008-07-24 Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355.
    2008-05-01 抗腫瘤化合物 I296195/2008-05-01
    2008-02 A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells Anti-Cancer Drugs. 2008 Feb;19(2):151-158.
    2007-11-15 Tamoxifen accelerates proteasomal degradation of O-6-methylguanine DNA methyltransferase in human cancer cells International Journal of Cancer. 2007 Nov;121(10):2293-2300.
    2007-10 A novel oral indoline-sulfonamide agent, N-[1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-Isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule Journal of Pharmacology and Experimental Therapeutics. 2007 Oct;323(1):398-405.
    2007-10 Human tissue kallikreins as prognostic biomarkers and as potential targets for anticancer therapy Expert Opinion on Therapeutic Patents. 2007 Oct;17(10):1227-1240.
    2007-09-06 4-and 5-aroylindoles as novel classes of potent antitubulin agents Journal of Medicinal Chemistry. 2007 Sep;50(18):4548-4552.

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