國家衛生研究院 NHRI:Item 3990099045/2378
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/2378


    Title: Levels of polychlorinated dibenzo-p-dioxins and dibenzofurans in primipara breast milk from Taiwan: estimation of dioxins and furans intake for breastfed infants
    Authors: Chao, HR;Wang, SL;Su, PH;Yu, HY;Yu, ST;Papke, O
    Contributors: Division of Environmental Health and Occupational Medicine
    Abstract: Postnatal exposure to dioxins in breastfed infants occurs mainly during breast-feeding. The exposure to a substantial amount of endocrine disruptors in the early days of life may cause long-term health effects. Test subjects were healthy and primiparous mothers with a mean age of 28 (S.D. = 3.8) in 2001. The PCDD/F congeners were analyzed in the breast milk using gas chromatograph/high resolution mass spectrometry. The mean level of PCDD/Fs was 7.4 pg-WHO-TEQ/g lipid, which is significantly lower than the level found in individuals from other countries. The total PCDD WHO-TEQ levels in breast milk had a significant positive association with maternal age and a slightly negative association with perinatal BMI (body mass index of the period before and after the delivery). The estimated daily intake of 10.5 pg-WHO-TEQ/kg/day from individual breast milk was predicted for a breastfed infant at 6 months of age with proper assumption of 8 kg body weight, 854 g milk per day of consumption, 95 % of dioxin absorption rate, and linear decline of dioxin during lactation. Based on the lower WHO-TEQ levels in the breast milk, breast-feeding should still be encouraged and continued in Taiwan.
    Keywords: Engineering, Environmental;Engineering, Civil;Environmental Sciences
    Date: 2005-05-20
    Relation: Journal of Hazardous Materials. 2005 May;121(1-3):1-10.
    Link to: http://dx.doi.org/10.1016/j.jhazmat.2004.09.021
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0304-3894&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000229556500001
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=18844406004
    Appears in Collections:[Shu-Li Wang] Periodical Articles

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