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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/2484


    Title: Prevalence of non-insulin-dependent diabetes mellitus and related vascular diseases in southwestern Arseniasis-endemic and nonendemic areas in Taiwan
    Authors: Wang, SL;Chiou, JM;Chen, CJ;Tseng, CH;Chou, WL;Wang, CC;Wu, TN;Chang, LW
    Contributors: Division of Environmental Health and Occupational Medicine;Division of Biostatistics and Bioinformatics
    Abstract: There is evidence indicating that ingestion of arsenic may predispose the development of diabetes mellitus in arsenic-endemic areas in Taiwan. However, the prevalence of diabetes and related vascular diseases in the entire southwestern arseniasis-endemic and nonendemic areas remains to be elucidated. We used the National Health Insurance Database for 1999-2000 to derive the prevalence of non-insulin-dependent diabetes and related vascular diseases by age and sex among residents in southwestern arseniasis-endemic and nonendemic areas in Taiwan. The study included 66,667 residents living in endemic areas and 639,667 in nonendemic areas, all ! 25 years of age. The status of diabetes and vascular diseases was ascertained through disease diagnosis and treatment prescription included in the reimbursement claims of clinics and hospitals. The prevalence of non-insulin-dependent diabetes, age- and gender-adjusted to the general population in Taiwan, was 7.5% (95% confidence interval, 7.4-7.7%) in the arseniasis- endemic areas and 3.5% (3-5-3.6%) in the nonendemic areas. Among both diabetics and nondiabetics, higher prevalence of microvascular and macrovascular diseases was observed in arseniasis-endemic than in the nonendemic areas. Age- and gender-adjusted prevalence of microvascular disease in endemic and nonendemic areas was 20.0% and 6.0%, respectively, for diabetics, and 8.6% and 1.0%, respectively, for nondiabetics. The corresponding prevalence of macrovascular disease was 25.3% and 13.7% for diabetics, and 12.3% and 5.5% for nondiabetics. Arsenic has been suggested to increase the risk of non-insulin-dependent diabetes mellitus and its related micro- and macrovascular diseases.
    Keywords: Environmental Sciences;Public, Environmental & Occupational Health
    Date: 2003-02
    Relation: Environmental Health Perspectives. 2003 Feb;111(2):155-159.
    Link to: http://dx.doi.org/10.1289/ehp.5457
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0091-6765&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000180963400026
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0037294438
    Appears in Collections:[張惠華(1999-2009)] 期刊論文
    [丘政民(2000-2004)] 期刊論文
    [王淑麗] 期刊論文

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