國家衛生研究院 NHRI:Item 3990099045/2801
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    題名: Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana
    作者: Chien, SC;Chang, JY;Kuo, CC;Hsieh, CC;Yang, NS;Kuo, YH
    貢獻者: National Institute of Cancer Research
    摘要: The novel skeleton compounds, chamaecypanone C (3) and obtunorlignan A (4) were isolated from the heartwood of Chamaecyparis obtusa var. formosana. The structure of 3 was elucidated as a dimeric of monoterpene and norlignan with tricyclo- [5.2.2.0(2.6)]undecane and the structure of 4 was elucidated as a norlignan skeleton by spectroscopic methods. Compound 3 exhibits potent cytotoxic activity against several human cancer cells with IC50 values ranging from 0.19 to 0.52 mu M, whereas 4 has no activity. (c) 2007 Published by Elsevier Ltd.
    關鍵詞: Chemistry, Organic
    日期: 2007-02-26
    關聯: Tetrahedron Letters. 2007 Feb;48(9):1567-1569.
    Link to: http://dx.doi.org/10.1016/j.tetlet.2007.01.011
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0040-4039&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000244536200011
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33846625183
    顯示於類別:[郭靜娟] 期刊論文
    [張俊彥] 期刊論文

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