國家衛生研究院 NHRI:Item 3990099045/3117
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    题名: A study of anthropomorphic and biochemical characteristics in girls with central precocious puberty and thelarche variant
    作者: Su, PH;Wang, SL;Chen, JY;Chen, SJ;Ke, JC
    贡献者: Division of Environmental Health and Occupational Medicine
    摘要: Background. Premature thelarche in later childhood may progress to central precocious puberty (CPP), which does not spontaneously resolve. Thelarche variant (TV) is a slowly progressive variant of precocious puberty. Aim: To determine and compare levels of insulin-like growth factor-I (IGF-I), IGF binding protein-3 (IGFBP-3) and anthropomorphic measures in girls with TV and CPP. Subjects: Prepubertal controls and girls with TV and CPP. Methods: Chronological and bone age, weight, height, BMI, height velocity (HV), and serum IGF-I, IGFBP-3, leptin, follicle-stimulating hormone (FSH) and lutenizing hormone (LH) levels were assessed. Results: Serum IGF-I levels, HV and IGF-I/IGFBP-3 ratio were significantly higher in girls with CPP compared to both controls and girls with TV. IGFBP-3 values for bone age (IGFBP-3(BA)) were significantly higher in the TV group compared to both controls and girls with CPP. FSH and LH concentrations were significantly higher in the CPP group compared to TV. Conclusion: HV, IGF-I, LH and FSH levels and IGF-I/IGFBP-3 ratio are elevated in girls with CPP compared to those with TV.
    关键词: Endocrinology & Metabolism;Pediatrics
    日期: 2008-03
    關聯: Journal of Pediatric Endocrinology and Metabolism. 2008 Mar;21(3):213-220.
    Link to: https://doi.org/10.1515/JPEM.2008.21.3.213
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0334-018X&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000255295100004
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=42449101187
    显示于类别:[王淑麗] 期刊論文

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