國家衛生研究院 NHRI:Item 3990099045/3428
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    题名: Host factors do not influence the colonization or infection by fluconazole resistant Candida species in hospitalized patients
    作者: Yang, YL;Cheng, MF;Chang, YW;Young, TG;Chi, H;Lee, SC;Cheung, BMH;Tseng, FC;Chen, TC;Ho, YH;Shi, ZY;Chan, CHH;Lin, JY;Lo, HJ
    贡献者: Division of Clinical Research
    摘要: Nosocomial yeast infections have significantly increased during the past two decades in industrialized countries, including Taiwan. This has been associated with the emergence of resistance to fluconazole and other antifungal drugs. The medical records of 88 patients, colonized or infected with Candida species, from nine of the 22 hospitals that provided clinical isolates to the Taiwan Surveillance of Antimicrobial Resistance of Yeasts (TSARY) program in 1999 were reviewed. A total of 35 patients contributed fluconazole resistant strains [minimum inhibitory concentrations (MICs) ? 64 mg/l], while the remaining 53 patients contributed susceptible ones (MICs % 8 mg/l). Fluconazole resistance was more frequent among isolates of Candida tropicalis (46.5%) than either C. albicans (36.8%) or C. glabrata (30.8%). There was no significant difference in demographic characteristics or underlying diseases among patients contributing strains different in drug susceptibility. ? 2008 Yang et al; licensee BioMed Central Ltd.
    日期: 2008-12
    關聯: Journal of Negative Results in BioMedicine. 2008 Dec;7:12.
    Link to: http://dx.doi.org/10.1186/1477-5751-7-12
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=58249104010
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