國家衛生研究院 NHRI:Item 3990099045/3548
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    题名: CNVVdb: A database of copy number variations across vertebrate genomes
    作者: Chen, FC;Chen, YZ;Chuang, TJ
    贡献者: Division of Biostatistics and Bioinformatics
    摘要: Summary: CNVVdb is a web interface for identification of putative copy number variations (CNVs) among 16 vertebrate species using the-same-species self-alignments and cross-species pairwise alignments. By querying genomic coordinates in the target species, all the potential paralogous/orthologous regions that overlap ?80-100% (adjustable) of the query sequences with user-specified sequence identity (?60%??90%) are returned. Additional information is also given for the genes that are included in the returned regions, including gene description, alternatively spliced transcripts, gene ontology descriptions and other biologically important information. CNVVdb also provides information of pseudogenes and single nucleotide polymorphisms (SNPs) for the CNV-related genomic regions. Moreover, multiple sequence alignments of shared CNVs across species are also provided. With the combination of CNV, SNP, pseudogene and functional information, CNVVdb can be very useful for comparative and functional studies in vertebrates.
    日期: 2009-06
    關聯: Bioinformatics. 2009 Jun;25(11):1419-1421.
    Link to: http://dx.doi.org/10.1093/bioinformatics/btp166
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1367-4803&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000266109500012
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=65649083003
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