國家衛生研究院 NHRI:Item 3990099045/3632

NHRI > National Institute of Environmental Health Sciences > Ying-Chin Ko(2003-2009) > Periodical Articles > Item 3990099045/3632

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/3632

Title:	Consumption of cigarettes but not betel quid or alcohol increases colorectal cancer risk
Authors:	Wu, IC;Lee, CH;Kuo, CH;Kuo, FC;Wu, DC;Ko, YC;Yu, FJ
Contributors:	Division of Environmental Health and Occupational Medicine
Abstract:	Background/Purpose: The effect of betel quid chewing on colorectal cancer (CRC) risk has not been reported. In addition, there is no consensus about the causal relationship between smoking or alcohol consumption and CRC risk. This study investigated the impact of betel quid chewing, cigarette smoking or alcohol consumption on CRC risk in Taiwan. Methods: Two hundred and fifty-eight patients with pathologically proven CRC (153 men, 105 women; mean age, 63.1 years) were recruited from two hospitals in southern Taiwan. The controls were 533 age-and gender-matched cancer-free subjects from the same hospitals. All subjects were interviewed using a standardized questionnaire to collect demographic and substance use data. Results: After adjusting for potential confounding factors, smoking (adjusted odds ratio [aOR], 1.65; 95% CI, 1.1-2.3), but not betel quid chewing (aOR, 1.3; 95% CI, 0.7-2.4) or alcohol drinking (aOR, 1.1; 95% CI, 0.7-1.8), was an independent significant risk factor for developing CRC. The significant risk effect of smoking was seen mainly among men, because the frequency of smokers was much higher among Taiwanese men than women. Conclusion: Our results indicated that consumption of cigarettes but not betel quid or alcohol was a risk factor for male CRC. A large study is necessary to investigate the risk factors for female CRC in Taiwan, and to understand the effect of betel quid exposure on male CRC.
Date:	2009-02
Relation:	Journal of the Formosan Medical Association. 2009 Feb;108(2):155-163.
Link to:	http://dx.doi.org/10.1016/S0929-6646(09)60046-2
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0929-6646&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000264033900009
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=63049120024
Appears in Collections:	[Ying-Chin Ko(2003-2009)] Periodical Articles

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