國家衛生研究院 NHRI:Item 3990099045/3738
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12500/13673 (91%)
造訪人次 : 2560578      線上人數 : 201
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/3738


    題名: Sampling strategies for occupational exposure assessment under generalized linear model
    作者: Chen, CC;Chuang, CL;Wu, KY;Chan, CC
    貢獻者: Division of Biostatistics and Bioinformatics
    摘要: Objectives: Occupational exposure assessment is a major task in industrial hygiene studies. Although statistical analyses for magnitudes and variations of exposures to various types of working populations based on existing data sets are extensive, relatively few discussions on study designs appear in the literature, especially for sample size determination and number of repeated measurements.Methods: In this paper, we propose a general framework of sampling strategies on sample size requirement together with the number of repeated measurements using the mixed-effects generalized linear model (GLM). As illustrative examples, we discuss sampling strategies separately under the log-normal assumption for hypotheses testing on (i) mean exposure differences of multiple worker groups and (ii) presence of a long-term exposure trend.Results: Given a specified alternative hypothesis, the desired significance level and statistical power, the number of repeated measurements, within-worker and between-worker variances, and a correlation structure, we have derived and tabulated an explicit sample size requirement of the two hypothetical cases under log-normal distribution assumption.Conclusions: On the basis of the tabulated outcomes, the sample size requirement is much more dominant than the number of repeated measurements for a group exposure comparison. Thus, in this case, recruiting more workers with fewer repeated measurements may be more economical than the opposite approach. For testing the presence of a long-term exposure trend, the sample size required decreases substantially with the number of repeated measurements. Also, equally spaced sampling times would be optimal because the effect of between-worker variance is algebraically cancelled out in sample size calculations.
    日期: 2009-07
    關聯: Annals of Occupational Hygiene. 2009 Jul;53(5):509-521.
    Link to: http://dx.doi.org/10.1093/annhyg/mep034
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000267665800007
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=68149120422
    顯示於類別:[陳主智] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    SCP68149120422.pdf186KbAdobe PDF1213檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋