The genetic structure of beta-lactamases in Acinetobacter genospecies 3 (AG3) Taiwan isolates was studied for their high resistant rates to beta-lactams, including carbapenems (57.9%). The blaIMP-1 and blaIMP-8 were located in class 1 integron. The blaOXA-58 was bracketed by ISAba3. A novel TnpF-like integrase gene was identified upstream of the blaVEB-3. Before the 5' sequence of the blaADC, folE was identified. Four new ADC enzymes were found and clustered phylogenetically with published AG3 ADC proteins.
Date:
2010-06
Relation:
Antimicrobial Agents and Chemotherapy. 2010 Jun;54(6):2699-2703.
