國家衛生研究院 NHRI:Item 3990099045/4430
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4430


    Title: A Bayes regression approach to array-CGH data
    Authors: Wen, CC;Wu, YJ;Huang, YH;Chen, WC;Liu, SC;Jiang, SS;Juang, JL;Lin, CY;Fang, WT;Hsiung, CA;Chang, IS
    Contributors: National Institute of Cancer Research;Division of Biostatistics and Bioinformatics;Division of Molecular and Genomic Medicine
    Abstract: This paper develops a Bayes regression model having change points for the analysis of array-CGH data by utilizing not only the underlying spatial structure of the genomic alterations but also the observation that the noise associated with the ratio of the fluorescence intensities is bigger when the intensities get smaller. We show that this Bayes regression approach is particularly suitable for the analysis of cDNA microarray-CGH data, which are generally noisier than those using genomic clones. A simulation study and a real data analysis are included to illustrate this approach.
    Date: 2006-02
    Relation: Statistical Applications in Genetics and Molecular Biology. 2006 Feb;5(1):Article number 3.
    Link to: http://dx.doi.org/10.2202/1544-6115.1149
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2194-6302&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000202958400003
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33646352945
    Appears in Collections:[I-Shou Chang] Periodical Articles
    [Chao A. Hsiung] Periodical Articles
    [Jyh-Lyh Juang] Periodical Articles
    [Shih-Sheng Jiang] Periodical Articles
    [Chung-Yen Lin(1999-2005)] Periodical Articles

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