國家衛生研究院 NHRI:Item 3990099045/4478
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    題名: Immunofluorescence assay for detection of the nucleocapsid antigen of the severe acute respiratory syndrome (SARS) - Associated coronavirus in cells derived from throat wash samples of patients with SARS
    作者: Liu, IJ;Chen, PJ;Yeh, SH;Chiang, YP;Huang, LM;Chang, MF;Chen, SY;Yang, PC;Chang, SC;Wang, WK;Coll, SRGNTU
    貢獻者: Division of Molecular and Genomic Medicine
    摘要: An antigen detection assay for severe acute respiratory syndrome (SARS) coronavirus was established in this study by an indirect immunofluorescence test, which utilized cells derived from throat wash samples of patients with SARS and a rabbit serum that recognized the nucleocapsid protein of SARS-associated coronavirus (SARS-CoV) but not that of other human coronavirus tested. It detected SARS-CoV in 11 of 17 (65%) samples from SARS patients as early as day 2 of illness but in none of the 10 samples from healthy controls. Compared with other diagnostic modalities for detecting SARS-CoV, this assay is simpler, more convenient, and economical. It could be an alternative for early and rapid diagnosis, should SARS return in the future.
    日期: 2005-05
    關聯: Journal of Clinical Microbiology. 2005 May;43(5):2444-2448.
    Link to: http://dx.doi.org/10.1128/jcm.43.5.2444-2448.2005
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0095-1137&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000229090100061
    Cited Times(Scopus): https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84983724699
    顯示於類別:[葉秀慧(2001-2005)] 期刊論文

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