國家衛生研究院 NHRI:Item 3990099045/4528
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4528


    Title: Construction and analysis of a human-chimpanzee comparative clone map
    Authors: Fujiyama, A;Watanabe, H;Toyoda, A;Taylor, TD;Itoh, T;Tsai, SF;Park, HS;Yaspo, ML;Lehrach, H;Chen, Z;Fu, G;Saitou, N;Osoegawa, K;de Jong, PJ;Suto, Y;Hattori, M;Sakaki, Y
    Contributors: Division of Molecular and Genomic Medicine
    Abstract: The recently released human genome sequences provide us with reference data to conduct comparative genomic research on primates, which will be important to understand what genetic information makes us human. Here we present a first-generation human-chimpanzee comparative genome map and its initial analysis. The map was constructed through paired alignment of 77,461 chimpanzee bacterial artificial chromosome end sequences with publicly available human genome sequences. We detected candidate positions, including two clusters on human chromosome 21 that suggest large, nonrandom regions of difference between the two genomes.
    Date: 2002-01
    Relation: Science. 2002 Jan;295(5552):131-134.
    Link to: http://dx.doi.org/10.1126/science.1065199
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0036-8075&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000173143100050
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0037016456
    Appears in Collections:[Shih-Feng Tsai] Periodical Articles

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