2011-03-07 |
2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors |
ChemMedChem. 2011 Mar 7;6(3):450-456. |
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2011-01-26 |
Labdanecaryophyllic acid, a novel cytotoxic C35 terpenoid from Calocedrus macrolepis var. formosana |
Tetrahedron Letters. 2011 Jan 26;52(4):515-517. |
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2010-08 |
Synthesis and biological evaluation of 7-arylindoline-1-benzenesulfonamides as a novel class of potent anticancer agents |
MedChemComm. 2010 Aug;1(2):152-155. |
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2010-06-18 |
Cytotoxic C35 terpenoid cryptotrione from the bark of cryptomeria japonica |
Organic Letters. 2010 Jun;12(12):2786-2789. |
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2010-06 |
Design and synthesis of alpha-ketoamides as cathepsin S inhibitors with potential applications against tumor invasion and angiogenesis |
Journal of Medicinal Chemistry. 2010 Jun;53(11):4545-4549. |
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2010-05 |
Chamaecypanone C, a novel skeleton microtubule inhibitor, with anticancer activity by trigger caspase 8-Fas/FasL dependent apoptotic pathway in human cancer cells |
Biochemical Pharmacology. 2010 May;79(9):1261-1271. |
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2010-04 |
Arecoline arrests cells at prometaphase by deregulating mitotic spindle assembly and spindle assembly checkpoint: Implication for carcinogenesis |
Oral Oncology. 2010 Apr;46(4):255-262. |
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2010-03-11 |
5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors |
Journal of Medicinal Chemistry. 2010 Mar 11;53(5):2309-2313. |
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2009-11-01 |
Effects of drying and extrusion on colour, chemical composition, antioxidant activities and mitogenic response of spleen lymphocytes of sweet potatoes |
Food Chemistry. 2009 Nov 1;117(1):114-121. |
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2009-08-13 |
Synthesis and evaluation of 3-aroylindoles as anticancer agents: Metabolite approach |
Journal of Medicinal Chemistry. 2009 Aug 13;52(15):4941-4945. |
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2009-07-23 |
Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity |
Journal of Medicinal Chemistry. 2009 Jul 23;52(14):4221-4233. |
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2009-07-03 |
Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers |
Molecular Cancer. 2009 Jul 3;8:Article number 43. |
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2009-04-17 |
Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents |
ChemMedChem. 2009 Apr 17;4(4):588-593. |
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2008-12-25 |
Synthesis and structure-activity relationships of 2-amino-1-aroylnaphthalene and 2-hydroxy-1-aroylnaphthalenes as potent antitubulin agents |
Journal of Medicinal Chemistry. 2008 Dec 25;51(24):8163-8167. |
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2008-08 |
Transcriptional repression of O-6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N '-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells |
Molecular Pharmacology. 2008 Aug;74(2):517-526. |
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2008-07-24 |
Discovery of 4-amino and 4-hydroxy-1-aroylindoles as potent tubulin polymerization inhibitors |
Journal of Medicinal Chemistry. 2008 Jul;51(14):4351-4355. |
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2008-02 |
A novel peroxisome proliferator-activated receptor alpha/gamma agonist, BPR1H0101, inhibits topoisomerase II catalytic activity in human cancer cells |
Anti-Cancer Drugs. 2008 Feb;19(2):151-158. |
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2007-11-15 |
Tamoxifen accelerates proteasomal degradation of O-6-methylguanine DNA methyltransferase in human cancer cells |
International Journal of Cancer. 2007 Nov;121(10):2293-2300. |
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2007-10 |
A novel oral indoline-sulfonamide agent, N-[1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-Isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule |
Journal of Pharmacology and Experimental Therapeutics. 2007 Oct;323(1):398-405. |
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2007-09-06 |
4-and 5-aroylindoles as novel classes of potent antitubulin agents |
Journal of Medicinal Chemistry. 2007 Sep;50(18):4548-4552. |
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2007-07-31 |
Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil |
British Journal of Cancer. 2007 Jul;97(3):334-344. |
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2007-02-26 |
Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana |
Tetrahedron Letters. 2007 Feb;48(9):1567-1569. |
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2007-01 |
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation |
Molecular Cancer Therapeutics. 2007 Jan;6(1):193-202. |
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2006-11-27 |
C-35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines |
Journal of Natural Products. 2006 Nov;69(11):1611-1613. |
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2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents |
Journal of Medicinal Chemistry. 2006 Nov;49(23):6656-6659. |
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