國家衛生研究院 NHRI:Item 3990099045/4815

NHRI > Center for Neuropsychiatric Research > Keh-Ming Lin(2004-2009) > Conference Papers/Meeting Abstract > Item 3990099045/4815

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/4815

Title:	Characteristics associated with benzodiazepine usage in elderly outpatients in Taiwan
Authors:	Cheng, JS;Huang, WF;Lin, KM;Shih, YT
Contributors:	Division of Mental Health and Addiction Medicine;Division of Health Policy Research and Development
Abstract:	OBJECTIVES: Benzodiazepines are commonly prescribed forolder people. As the elderly are more susceptible to potentialadverse outcomes from benzodiazepines, it is recommended thatbenzodiazepines be used for short periods with a reduced dosage.This observational study aimed to investigate benzodiazepineuse, in terms of treatment period and mean dosage, and examinecharacteristics associated with use. METHODS: This was anobservational study of randomly selected subjects enrolled in theNational Health Insurance program, aged at least 65, whoreceived at least one prescription for benzodiazepines in 2002.They were grouped according to treatment period and meandosage. The treatment period was deﬁned as the number of dayscovered by prescribed benzodiazepines. The mean dosage wasdeﬁned by the average deﬁned daily dose (DDD) of each indi-vidual. An ordered logit regression model was adopted to eval-uate associations of characteristics with benzodiazepine usage.RESULTS: Of the 17,024 elderly persons included, a total of7451 had received at least one prescription for benzodiazepines.Individuals with comorbid mental disease such as insomnia,anxiety, and depression, and comorbid physical disease such ascardiovascular disease, cancer, and renal disease, and previousreceipt of benzodiazepines were more likely to receive benzodi-azepine prescriptions. Those older than 75 years, male, withinsomnia, anxiety, depression, mental disease, physical diseasesuch as cardiovascular disease and diabetes, previous receipt ofbenzodiazepines, and higher prescription-overlap ratio weremore likely to receive longer treatment. Subjects with insomnia,anxiety, depression, other mental disease, arthritis, previousreceipt of more benzodiazepines, and higher prescription-overlapratio were more likely to receive higher-dose therapy. CON-CLUSION: According to our preliminary ﬁndings, the one-yearprevalence of benzodiazepine use among the elderly was approx-imately 44%. Mental disorders, previous exposure to more benzodiazepine, and higher prescription-overlap ratio were asso-ciated with both longer treatment and higher mean daily dose.
Date:	2007-05
Relation:	Value in Health. 2007 May-Jun;10(3):A157.
Link to:	http://dx.doi.org/10.1016/S1098-3015(10)69016-X
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1098-3015&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000246714800491
Appears in Collections:	[Keh-Ming Lin(2004-2009)] Conference Papers/Meeting Abstract [Yaw-Tang Shih(1999-2006)] Conference Papers/Meeting Abstract

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