國家衛生研究院 NHRI:Item 3990099045/4838
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    题名: A voxel-based partial volume correction in nuclear medicine
    其它题名: Medical Imaging 2006: Image Processing
    作者: Huang, HM;Hsiao, IT;Wietholt, C;Hsu, CH
    贡献者: Division of Medical Engineering Research
    摘要: Most partial volume correction (PVC) methods are ROI-based, and assume uniform activity within each ROI. Here, we extended a PVC method, developed by Roussel et al (JNM, 1998) called geometric transfer matrix (GTM), to a voxel-based PVC approach called v-GTM which accounts non-uniform activity within each ROI. The v-GTM method was evaluated using simulated data (perfect co-registered MRIs). We investigated the influence of noise, the effect of compensating detector response during iterative reconstruction methods and the effect of non-uniform activity. For simulated data, noise did not affect the accuracy of v-GTM method seriously. When detector response compensation was applied in iterative reconstruction, both PVC methods did not improve the recovery values. In the non-uniform experiment, v-GTM had slightly better recovery values and less bias than those of GTM. Conclusion: v-GTM resulted better recovery values, and might be useful for PVC in small regions of interest.
    日期: 2006-03
    關聯: Proceedings of the Society of Photo-Optical Instrumentation Engineers(SPIE). 2006;6144(Part 1-3):P1446.
    Link to: http://dx.doi.org/10.1117/12.654273
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000238033302075
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33745123336
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