國家衛生研究院 NHRI:Item 3990099045/4839
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12189/12972 (94%)
造訪人次 : 967930      線上人數 : 829
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/4839


    題名: A novel model of the geometric and detector response for limited angular sampling pinhole SPECT
    其他題名: Medical Imaging 2006: Physics of Medical Imaging
    作者: Wietholt, C;Hsiao, IT;Clough, AV;Chen, CT
    貢獻者: Division of Medical Engineering Research
    摘要: Reconstruction methodologies for data sets with reduced angular sampling (RAS) are essential for efficient dynamic or static preclinical animal imaging research using single photon emission computed tomography (SPECT). Modern iterative reconstruction methods can obtain 3D radiotracer distributions of the highest possible quality and resolution. Essential to these algorithms is an accurate model of the physical imaging process. We developed a new point-spread function (PSF) model for the pinhole geometry and compared it to a Gaussian model in a RAS setting. The new model incorporates the geometric response of the pinhole and the detector response of the camera by simulating the system PSF using the error function. Reconstruction of simulated data was done with OS-EM and COS-EM: a new convergent OS-EM based algorithm. The reconstruction of projection data of a simulated point source using the novel method showed improved FWHM values compared to a standard Gaussian method. COS-EM delivers improved results for RAS data, although it converges slower than OS-EM. The reconstruction of Monte Carlo simulated projection data from a resolution phantom shows that as few as 40 projections are sufficient to reconstruct an image with a resolution of approximately 4 mm. The new pinhole model applied to iterative reconstruction methods can reduce imaging time in small animal experiments by a factor of three or reduce the number of cameras needed to perform dynamic SPECT.
    日期: 2006-03
    關聯: Proceedings of the Society of Photo-Optical Instrumentation Engineers(SPIE). 2006;6142(Part 1-3):14253.
    Link to: http://dx.doi.org/10.1117/12.653016
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000238049700173
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=33745399242
    顯示於類別:[其他] 會議論文/會議摘要

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    SCP33745399242.pdf768KbAdobe PDF197檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋