邻近类别 會議論文/會議摘要 [0/1] 类别统计 近3年内发表的文件:5(20.83%) 含全文笔数:24(100.00%) 文件下载次数统计 下载大于0次:24(100.00%) 下载大于100次:22(91.67%) 全文下载总次数:12179(100.00%) 最后更新时间: 2024-12-01 11:09 上传排行 数据加载中..... 下载排行 数据加载中..... 最近上传 DBPR116, a prodrug of BPRMU191, in ... Discovery of a mu-opioid receptor m... A dual nociceptin and mu opioid rec... Benzo[b]thiophene-2-carboxamides as... Selective and antagonist-dependent ... Comparative study between deep lear... Increased activation of HDAC1/2/6 a... Betulinic acid-mediated tuning of P... Morphine produces potent antinocice... BPR1M97, a dual mu opioid receptor/...

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日期	题名	關聯
2024-10-29	DBPR116, a prodrug of BPRMU191, in combination with naltrexone as a safer opioid analgesic than morphine via peripheral administration	Journal of Medicinal Chemistry. 2024 Oct 29;Article in Press.
2024-07-17	Discovery of a mu-opioid receptor modulator that in combination with morphinan antagonists induces analgesia	Cell Chemical Biology. 2024 Jul 17;Article in Press.
2023-10-05	A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects	European Journal of Medicinal Chemistry. 2023 Oct 05;258:Article number 115608.
2022-12-05	Benzo[b]thiophene-2-carboxamides as novel opioid receptor agonists with potent analgesic effect and reduced constipation	European Journal of Medicinal Chemistry. 2022 Dec 5;243:Article number 114728.
2022-11	Selective and antagonist-dependent µ-opioid receptor activation by the combination of 2-{[2-(6-chloro-3,4-dihydro-1(2H)-quinolinyl)-2-oxoethyl]sulfanyl}-5-phenyl-4,6-(1H,5H)-pyrimidinedione and naloxone/naltrexone	Bioorganic Chemistry. 2022 Nov;128:Article number 105905.
2020-10-08	Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery	Scientific Reports. 2020 Oct 8;10:Article number 16771.
2020-10	Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma	Neuro-Oncology. 2020 Oct;22(10):1439-1451.
2020-06	Morphine produces potent antinociception, sedation, and hypothermia in humanized mice expressing human mu opioid receptor splice variants	Pain. 2020 Jun;161(6):1177-1190.
2020-04-15	Betulinic acid-mediated tuning of PERK/CHOP signaling by Sp1 inhibition as a novel therapeutic strategy for glioblastoma	Cancers. 2020 Apr 15;12(4):Article number 981.
2020-04	BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine	Neuropharmacology. 2020 Apr;166:Article number 107678.

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