| 2007-10 |
A novel oral indoline-sulfonamide agent, N-[1-(4-Methoxy-benzenesulfonyl)-2,3-dihydro-1H-indol-7-yl]-Isonicotinamide (J30), exhibits potent activity against human cancer cells in vitro and in vivo through the disruption of microtubule |
Journal of Pharmacology and Experimental Therapeutics. 2007 Oct;323(1):398-405. |
 |
| 2007-10 |
Human tissue kallikreins as prognostic biomarkers and as potential targets for anticancer therapy |
Expert Opinion on Therapeutic Patents. 2007 Oct;17(10):1227-1240. |
|
| 2007-09-06 |
4-and 5-aroylindoles as novel classes of potent antitubulin agents |
Journal of Medicinal Chemistry. 2007 Sep;50(18):4548-4552. |
|
| 2007-07-31 |
Combined modalities of resistance in an oxaliplatin-resistant human gastric cancer cell line with enhanced sensitivity to 5-fluorouracil |
British Journal of Cancer. 2007 Jul;97(3):334-344. |
|
| 2007-03-01 |
Mitochondria-mediated and p53-associated apoptosis induced in human cancer cells by a novel selenophene derivative, D-501036 |
Biochemical Pharmacology. 2007 Mar;73(5):610-619. |
|
| 2007-02-26 |
Cytotoxic and novel skeleton compounds from the heartwood of Chamaecyparis obtusa var. formosana |
Tetrahedron Letters. 2007 Feb;48(9):1567-1569. |
|
| 2007-02-17 |
Lysosomal cysteine proteinase cathepsin S as a potential target for anti-cancer therapy |
Journal of Cancer Molecules. 2007 Feb 17;3(1):5-14. |
|
| 2007-01 |
D-501036, a novel selenophene-based triheterocycle derivative, exhibits potent in vitro and in vivo antitumoral activity which involves DNA damage and ataxia telangiectasia-mutated nuclear protein kinase activation |
Molecular Cancer Therapeutics. 2007 Jan;6(1):193-202. |
|
| 2006-12 |
Statistical quality control process for traditional Chinese medicine |
Journal of Biopharmaceutical Statistics. 2006 Dec;16(6):861-874. |
|
| 2006-11-27 |
C-35 terpenoids from the bark of Calocedrus macrolepis var. formosana with activity against human cancer cell lines |
Journal of Natural Products. 2006 Nov;69(11):1611-1613. |
|
| 2006-11-16 |
7-aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents |
Journal of Medicinal Chemistry. 2006 Nov;49(23):6656-6659. |
|
| 2006-11 |
Phase I and pharmacokinetic study of oral thalidomide in patients with advanced hepatocellular carcinoma |
Cancer Chemotherapy and Pharmacology. 2006 Nov;58(5):654-664. |
|
| 2006-10-19 |
2-amino and 2 '-aminocombretastatin derivatives as potent antimitotic agents |
Journal of Medicinal Chemistry. 2006 Oct;49(21):6412-6415. |
|
| 2006-10 |
Structure-activity relationship studies of 3-aroylindoles as potent antimitotic agents |
ChemMedChem. 2006 Oct;1(10):1106-1118. |
|
| 2006-09-25 |
Synthesis of new camptothecin analogues with the E-lactone ring replaced by alpha,beta-cyclohexenone |
European Journal of Organic Chemistry. 2006 Sep(19):4490-4499. |
|
| 2006-07-28 |
In vitro and in vivo studies of a novel potential anticancer agent of isochaihulactone on human lung cancer A549 cells |
Biochemical Pharmacology. 2006 Jul;72(3):308-319. |
|
| 2006-05 |
Antitubulin agents for the treatment of cancer - a medicinal chemistry update |
Expert Opinion on Therapeutic Patents. 2006 May;16(5):647-691. |
|
| 2006-05 |
Phase I study of biweekly gemcitabine followed by oxaliplatin and simplified 48-h infusion of fluorouracil/leucovorin for advanced pancreatic cancer |
Journal of Gastroenterology and Hepatology. 2006 May;21(5):874-879. |
|
| 2006-03 |
Phase I-II trial of weekly gemcitabine plus high-dose 5-fluorouracil and leucovorin in advanced pancreatic cancer |
Journal of Gastroenterology and Hepatology. 2006 Mar;21(3):531-536. |
|
| 2005-12-01 |
Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives |
Bioorganic and Medicinal Chemistry. 2005 Dec;13(23):6513-6520. |
|
| 2005-12 |
Pulmonary embolism after transcatheter arterial chemoembolization |
European Journal of Cancer Care. 2005 Dec;14(5):440-442. |
|
| 2005-09 |
Long-term complete remission of metastatic gastric cancer after weekly docetaxel, 24 h infusion of high-dose 5-FU/leucovorin and cisplatin |
Journal of Gastroenterology and Hepatology. 2005 Sep;20(9):1470-1471. |
|
| 2005-08-01 |
alpha-fetoprotein response predicts survival benefits of thalidomide in advanced hepatocellular carcinoma |
Alimentary Pharmacology and Therapeutics. 2005 Aug;22(3):217-226. |
|
| 2005-06 |
Hepatocellular carcinoma associated with acquired von Willebrand disease and extreme thrombocytosis |
Annals of Oncology. 2005 Jun;16(6):988-989. |
|
| 2005-02 |
Cytotoxic triterpenes from the aerial roots of Ficus microcarpa |
Phytochemistry. 2005 Feb;66(4):495-501. |
|
| 2005-01 |
Four new 6-Nor-5(6 →7)abeo-abietane type diterpenes and antitumoral cytotoxic diterpene constituents from the bark of Taiwania cryptomerioides |
Planta Medica. 2005 Jan;71(1):72-76. |
|
| 2004-08-12 |
Concise synthesis and structure-activity relationships of combretastatin A-4 analogues, 1-aroylindoles and 3-aroylindoles, as novel classes of potent antitubulin agents |
Journal of Medicinal Chemistry. 2004 Aug;47(17):4247-4257. |
|
| 2004-07-15 |
A novel bis-benzylidenecyclopentanone derivative, BPR0Y007, inducing a rapid caspase activation involving upregulation of Fas (CD95/APO-1) and wild-type p53 in human oral epidermoid carcinoma cells |
Biochemical Pharmacology. 2004 Jul;68(2):293-303. |
|
| 2004-07-01 |
BPR0L075, a novel synthetic indole compound with antimitotic activity in human cancer cells, exerts effective antitumoral activity in vivo |
Cancer Research. 2004 Jul;64(13):4621-4628. |
|
| 2004-05-20 |
Synthesis and structure-activity relationships of 3-aminobenzophenones as antimitotic agents |
Journal of Medicinal Chemistry. 2004 May;47(11):2897-2905. |
|
| 2004-01-01 |
Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells |
Molecular Pharmacology. 2004 Jan;65(1):77-84. |
|
| 2004-01 |
Three new oleanane-type triterpenes from Ludwigia octovalvis with cytotoxic activity against two human cancer cell lines |
Journal of Natural Products. 2004 Jan;67(1):91-93. |
|
| 2004 |
Hepatocellular carcinoma with intra-atrial tumor thrombi - A report of three cases responsive to thalidomide treatment and literature review |
Oncology. 2004;67(3-4):320-326. |
|
| 2003-11-17 |
New analogues of AHMA as potential antitumor agents: Synthesis and biological activity |
Bioorganic and Medicinal Chemistry. 2003 Nov;11(23):4959-4969. |
|
| 2003-06-15 |
Dual inhibition of topoisomerase I and tubulin polymerization by BPR0Y007, a novel cytotoxic agent |
Biochemical Pharmacology. 2003 Jun;65(12):2009-2019. |
|
| 2003-03-10 |
Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents (vol 13, pg 101, 2003) |
Bioorganic and Medicinal Chemistry Letters. 2003 Mar;13(5):977-977. |
|
| 2003-01-06 |
Structure-activity and crystallographic analysis of benzophenone derivatives - the potential anticancer agents |
Bioorganic and Medicinal Chemistry Letters. 2003 Jan;13(1):101-105. |
|
| 2002-10-09 |
2,2 '-diphenyl-1-picrylhydrazyl radical-scavenging active components from adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) hulls |
Journal of Agricultural and Food Chemistry. 2002 Oct;50(21):5850-5855. |
|
| 2002-09-26 |
Antitumor AHMA linked to DNA minor groove binding agents: Synthesis and biological evaluation |
Journal of Medicinal Chemistry. 2002 Sep;45(20):4485-4493. |
|
| 2002-07-01 |
Novel mutation of topoisomerase I in rendering cells resistant to camptothecin |
Cancer Research. 2002 Jul;62(13):3716-3721. |
|
| 2002-07 |
Non-surgical treatment for afferent loop syndrome in recurrent gastric cancer complicated by peritoneal carcinomatosis: percutaneous transhepatic duodenal drainage followed by 24-hour infusion of high-dose fluorouracil and leucovorin |
Annals of Oncology. 2002 Jul;13(7):1151-1155. |
|
| 2002-05 |
Phase II and pharmacokinetic study of GL331 in previously treated Chinese gastric cancer patients |
Cancer Chemotherapy and Pharmacology. 2002 May;49(5):425-428. |
|
| 2002 |
A phase I study of weekly docetaxel, 24-hour infusion of high-dose fluorouracil/leucovorin and cisplatin in patients with advanced gastric cancer |
Oncology. 2002;63(3):239-247. |
|
| 2000-03-01 |
Unique biochemical, cytotoxic, and antitumor activity of camptothecin and 4 beta-amino-4'-O-demethylepipodophyllotoxin conjugates |
Biochemical Pharmacology. 2000 Mar;59(5):497-508. |
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