國家衛生研究院 NHRI:
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    日期题名關聯
    2016-01 The role of wnt signaling in squamous cell carcinoma Journal of Dental Research. 2016 Jan;95(2):129-134.
    2016-01 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition Organic and Biomolecular Chemistry. 2016 Jan;14(2):716-723.
    2015-12 Novel oxime-bearing coumarin derivatives act as potent Nrf2/ARE activators in vitro and in mouse model European Journal of Medicinal Chemistry. 2015 Dec;106:60-74.
    2015-10 Integrating image-based high-content screening with mouse models identifies 5-hydroxydecanoate as a neuroprotective drug for paclitaxel-induced neuropathy Molecular Cancer Therapeutics. 2015 Oct ;14(10):2206-2214.
    2015-09 O6-Methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma International Journal of Cancer. 2015 Sep;137(6):1291-1305.
    2015-08 Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes Bioorganic and Medicinal Chemistry. 2015 Aug;23(15):4230-4236.
    2015-08 Novel Nrf2/ARE activator, trans-coniferylaldehyde, induces a HO-1-mediated defense mechanism through a dual p38alpha/MAPKAPK-2 and PK-N3 signaling pathway Chemical Research in Toxicology. 2015 Aug ;28(9):1681-1692.
    2015-07 Alcohol drinking obliterates the inverse association between serum retinol and risk of head and neck cancer Medicine. 2015 Jul;94(26):Article number e1064.
    2015-06-01 Autophagy-regulated ROS from xanthine oxidase acts as an early effector for triggering late mitochondria-dependent apoptosis in cathepsin S-targeted tumor cells PLoS ONE. 2015 Jun 1;10(6):Article number e0128045.
    2015-05 A KRAS mutation status-stratified randomized phase II trial of gemcitabine and oxaliplatin alone or in combination with cetuximab in advanced biliary tract cancer Annals of Oncology. 2015 May;26(5):943-949.
    2015-05 Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo Biochemical Pharmacology. 2015 May;95(1):28-37.
    2015-03 Genetic polymorphisms in the prostaglandin pathway genes and risk of head and neck cancer Oral Diseases. 2015 Mar;21(2):207-215.
    2015-03 Phase I study of nanoliposomal irinotecan (PEP02) in advanced solid tumor patients Cancer Chemotherapy and Pharmacology. 2015 Mar;75(3):579-586.
    2015-01 YM155 down-regulates survivin and XIAP, modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells British Journal of Pharmacology. 2015 Jan;172(1):214-234.
    2014-12-15 Downregulated miR329 and miR410 promote the proliferation and invasion of oral squamous cell carcinoma by targeting Wnt-7b Cancer Research. 2014 Dec 15;74(24):7560-7572.
    2014-12 Gelsolin regulates cisplatin sensitivity in human head-and-neck cancer International Journal of Cancer. 2014 Dec;135(12):2760-2769.
    2014-11 The interplay between alcohol consumption, oral hygiene, ALDH2 and ADH1B in the risk of head and neck cancer International Journal of Cancer. 2014 Nov;135(10):2424-2436.
    2014-10 DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model Gene Therapy. 2014 Oct;21(10):888-896.
    2014-09 Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents Bioorganic and Medicinal Chemistry. 2014 Sep;22(17):4917-4923.
    2014-08 CDKN1A-mediated responsiveness of MLL-AF4-positive acute lymphoblastic leukemia to Aurora kinase-A inhibitors International Journal of Cancer. 2014 Aug;135(3):751-762.
    2014-08 Downregulation of a putative tumor suppressor BMP4 by SOX2 promotes growth of lung squamous cell carcinoma International Journal of Cancer. 2014 Aug;135(4):809–819.
    2014-08 Chronic treatment with cisplatin induces replication-dependent sister chromatid recombination to confer cisplatin-resistant phenotype in nasopharyngeal carcinoma Oncotarget. 2014 Aug;5(15):6323-6337.
    2014-07 Inhibiting glucosylceramide synthase facilitates the radiosensitizing effects of vinorelbine in lung adenocarcinoma cells Cancer Letters. 2014 Jul;349(2):144-151.
    2014-05-05 Tea consumption and risk of head and neck cancer PLoS ONE. 2014 May 5;9(5):Article number e96507.
    2014-05 Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells Journal of Medicinal Chemistry. 2014 May;57(10):4009-4022.
    2014-04 Antimitotic and vascular disrupting agents: 2-hydroxy-3,4,5-trimethoxybenzophenones European Journal of Medicinal Chemistry. 2014 Apr 22;77(2):306-314.
    2014-04 Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib Cell Death and Disease. 2014 Apr;5:Article number e1162.
    2014-03 LRIG1 modulates aggressiveness of head and neck cancers by regulating EGFR-MAPK-SPHK1 signaling and extracellular matrix remodeling Oncogene. 2014 Mar;33(11):1375-1384.
    2014-02 A novel cancer therapeutic using thrombospondin 1 in dendritic cells Molecular Therapy. 2014 Feb;22(2):292-302.
    2014-01-10 Reciprocal regulation of MicroRNA-99a and insulin-like growth factor I receptor signaling in oral squamous cell carcinoma cells Molecular Cancer. 2014 Jan 10;13:Article number 6.
    2013-12 Autophagy induced by cathepsin S inhibition induces early ROS production, oxidative DNA damage, and cell death via xanthine oxidase Free Radical Biology and Medicine. 2013 Dec;65:1473-1486.
    2013-12 Mechanical regulation of cancer cell apoptosis and autophagy: Roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2013 Dec;1833(12):3124-3133.
    2013-10-16 Survivin - biology and potential as a therapeutic target in oncology Oncotargets and Therapy. 2013 Oct 16;6:1453-1462.
    2013-10 Gene expression profiling for analysis acquired oxaliplatin resistant factors in human gastric carcinoma TSGH-S3 cells: The role of IL-6 signaling and Nrf2/AKR1C axis identification Biochemical Pharmacology. 2013 Oct;86(7):872-887.
    2013-10 Investigating the association between oral hygiene and head and neck cancer Oral Oncology. 2013 Oct;49(10):1010-1017.
    2013-09 MPT0B169, a new tubulin inhibitor, inhibits cell growth and induces G2/M Arrest in nonresistant and paclitaxel-resistant cancer cells Pharmacology. 2013 Sep;92(1-2):90-98.
    2013-09 MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1α mrna through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR [Erratum: Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212.] Molecular Cancer Therapeutics. 2013 Sep;12(9):1919.
    2013-09 Furanylazaindoles: Potent anticancer agents in vitro and in vivo Journal of Medicinal Chemistry. 2013 Sep;56(20):8008-8018.
    2013-07-15 Microtubule-associated histone deacetylase 6 supports the calcium store sensor STIM1 in mediating malignant cell behaviors Cancer Research. 2013 Jul 15;73(14):4500-4509.
    2013-07 Epigenetic regulation of the X-linked tumour suppressors BEX1 and LDOC1 in oral squamous cell carcinoma Journal of Pathology. 2013 Jul;230(3):298-309.
    2013-07 MPT0B098, a novel microtubule inhibitor that destabilizes the hypoxia-inducible factor-1 alpha mRNA through decreasing nuclear-cytoplasmic translocation of RNA-binding protein HuR Molecular Cancer Therapeutics. 2013 Jul;12(7):1202-1212.
    2013-06-27 Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of the EGFR variant III and its clinical relevance Journal of Biomedical Science. 2013 Jun 27;20(1):Article number 43.
    2013-06-13 Cholestane-3beta, 5alpha, 6beta-triol suppresses proliferation, migration, and invasion of human prostate cancer cells PLoS ONE. 2013 Jun 13;8(6):Article number e65734.
    2013-05 Activation of PPAR-alpha induces cell cycle arrest and inhibits transforming growth factor-beta1 induction of smooth muscle cell phenotype in 10T1/2 mesenchymal cells Cellular Signalling. 2013 May;25(5):1252-1263.
    2013-04-24 Caffeic acid phenethyl ester suppresses proliferation and survival of TW2.6 human oral cancer cells via inhibition of Akt signaling International Journal of Molecular Sciences. 2013 Apr 24;14(5):8801-8817.
    2013-03-12 A novel synthetic microtubule inhibitor, MPT0B214 exhibits antitumor activity in human tumor cells through mitochondria-dependent intrinsic pathway PLoS ONE. 2013 Mar 12;8(3):Article number e58953.
    2013-02-01 Allergies and risk of head and neck cancer: An original study plus meta-analysis PLoS ONE. 2013 Feb 1;8(2):Article number e55138.
    2013-01 Randomised clinical trial: Comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma Alimentary Pharmacology and Therapeutics. 2013 Jan;37(1):62-73.
    2012-12 Arginine deprivation as a new treatment strategy for head and neck cancer Oral Oncology. 2012 Dec;48(12):1227-1235.
    2012-12 Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines Organic and Biomolecular Chemistry. 2012 Dec;10(48):9593-9600.

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