國家衛生研究院 NHRI:Item 3990099045/5301
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    题名: Cytotoxic Sesquiterpenes from Magnolia kachirachirai
    作者: Chang, HS;Lee, SJ;Yang, CW;Chen, IS
    贡献者: Institute of Biotechnology and Pharmaceutical Research
    摘要: Bioassay-guided fractionation of the root wood of Magnolia kachirachirai (KANEHIRA & YAMAMOTO) DANDY (Magnoliaceae) led to the isolation of three new compounds, kachiraterpenol (1), (E)-2,3-bis(4-hydroxy-3-methoxyphenyl)prop-2-enal (15), and kachiranol (19), together with 27 known compounds, of which 4,4'-dihydroxy-3,3'-dimethoxybenzophenone (16) was isolated for the first time from a natural source. Their structures were elucidated by spectroscopic analysis. Two of these isolates, costunolide (2) and dehydrosaussurea lactone (4), showed cytotoxic properties against MCF-7, NCI-H460, and SF-268 cancer cell lines in vitro.
    日期: 2010-11
    關聯: Chemistry and Biodiversity. 2010 Nov;7(11):2737-2747.
    Link to: http://dx.doi.org/10.1002/cbdv.200900418
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1612-1872&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000284967200008
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=78649239441
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