邻近类别 專利 [0/32] 期刊論文 [143/144] 类别统计 近3年内发表的文件:1(2.56%) 含全文笔数:27(69.23%) 文件下载次数统计 下载大于0次:27(100.00%) 下载大于100次:27(100.00%) 全文下载总次数:16042(15.51%) 最后更新时间: 2024-12-01 13:27 上传排行 数据加载中..... 下载排行 数据加载中..... 最近上传 Discovery of novel AXL and MER inhi... Targeting RSPO3 reduces stem cell f... Inhibition of Rspo-Wnt pathway faci... Discovery of clinical candidate DBP... Clinical candidate DBPR112: A novel... Targeting RSPO3 reduces stem cell f... Dendritic cell-derived exosomes inc... Discovery of 2,4-diaminopyrimidines... Optimization of quinazoline-based k... Discovery of BPR1K871-a quinazoline...

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日期	题名	關聯
2023-10	Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs	Annals of Oncology. 2023 Oct;34(Suppl. 2):S214.
2019-10	Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer	Annals of Oncology. 2019 Oct;30(Suppl. 5):789.
2019-10	Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117)	Annals of Oncology. 2019 Oct;30(Suppl. 5):191.
2018-12	Dendritic cell-derived exosomes increase the efficacy of anti-PD-L1 antibody in melanoma model	Cancer Science. 2018 Dec;109(Suppl. 2):1322.
2018-12	Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer	Cancer Science. 2018 Dec;109(SI, Suppl. 2):210.
2018-12	Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer	Cancer Science. 2018 Dec;109(Suppl. 2, SI):1257.
2018-07	Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer	Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789.
2018-01	Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer	Cancer Science. 2018 Jan;109(Suppl. 1):739.
2017-04	Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation	Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482.
2016-12	Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST	Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P.
2015-08	Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490.
2015-08	Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors	Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 182.
2014-11	Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent	European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93.
2014-10	Optimization of 5,6-fused pyrimidine-based kinase inhibitors by computer-aided drug design for the treatment of AML	Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 2530.
2014-10	Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma	Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 1756.
2014-03	DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study	Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 315-MEDI.
2014-03	Efficient virtual screening using ligand efficiency based approach	Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 55-MEDI.
2013-04-07	BPR000K, a novel Aurora kinase inhibitor	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI.
2013-04-07	3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI.
2013-04-07	Development drug candidate targeting EGFR kinase: DBPR112	Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI.
2013-04	Design and synthesis of Aurora kinase inhibitors as anticancer agents	Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI.
2012-11	BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia	European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54.
2012-03-25	Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors	Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI.
2011-09-23	BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo	European Journal of Cancer. 2011 Sep 23;47:S127.
2011-09	Overcoming the acquired resistance to Afatinib (BIBW2992) in HCC827, a non-small cell lung cancer cell line	European Journal of Cancer. 2011 Sep;47:S129.

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