| 2023-10 |
Discovery of novel AXL and MER inhibitors as potential anticancer and immune modulator drugs |
Annals of Oncology. 2023 Oct;34(Suppl. 2):S214. |
|
| 2019-10 |
Discovery of clinical candidate DBPR112, a furanopyrimidine-based epidermal growth factor receptor inhibitor for the treatment of non-small cell lung cancer |
Annals of Oncology. 2019 Oct;30(Suppl. 5):789. |
 |
| 2019-10 |
Inhibition of Rspo-Wnt pathway facilitates checkpoint blockade therapy by anti-RSPO3 antibody (DBPR117) |
Annals of Oncology. 2019 Oct;30(Suppl. 5):191. |
|
| 2018-12 |
Dendritic cell-derived exosomes increase the efficacy of anti-PD-L1 antibody in melanoma model |
Cancer Science. 2018 Dec;109(Suppl. 2):1322. |
|
| 2018-12 |
Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer |
Cancer Science. 2018 Dec;109(SI, Suppl. 2):210. |
|
| 2018-12 |
Targeting RSPO3 reduces stem cell function in RSPO3-Fusion-positive colon cancer and RSPO3 high lung cancer |
Cancer Science. 2018 Dec;109(Suppl. 2, SI):1257. |
|
| 2018-07 |
Clinical candidate DBPR112: A novel epidermal growth factor receptor inhibitor as a promising treatment for non-small cell lung cancer |
Cancer Research. 2018 Jul;78(13, Suppl.):Meeting Abstract 4789. |
|
| 2018-01 |
Discovery and development of DBPR112 as a clinical candidate: A novel EGFR inhibitor for non-small cell lung cancer |
Cancer Science. 2018 Jan;109(Suppl. 1):739. |
|
| 2017-04 |
Discovery of BPR1K871-a quinazoline based multi-kinase inhibitor for the treatment of AML and solid tumors: Rational design, synthesis, in vitro and in vivo evaluation |
Abstracts of Papers of the American Chemical Society. 2017 Apr;253:Meeting Abstract 482. |
|
| 2016-12 |
Novel cKIT kinase inhibitor, BPRCKJ001, as an advanced therapeutic candidate for GIST |
Annals of Oncology. 2016 Dec;27(Suppl. 9):Meeting Abstract 2P. |
|
| 2015-08 |
Optimization of quinazoline-based kinase inhibitors: Identification of a dual FLT3/AURKA kinase inhibitor for the treatment of acute myeloid leukemia |
Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 490. |
|
| 2015-08 |
Discovery of 2,4-diaminopyrimidines bearing a unique pharmacophore as anaplastic lymphoma kinase inhibitors |
Abstracts of Papers of the American Chemical Society. 2015 Aug;250:Meeting Abstract 182. |
|
| 2014-11 |
Discovery of multiple kinases inhibitors, DBPR114, as the novel anti-cancer agent |
European Journal of Cancer. 2014 Nov;50(Suppl. 6):92-93. |
|
| 2014-10 |
Optimization of 5,6-fused pyrimidine-based kinase inhibitors by computer-aided drug design for the treatment of AML |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 2530. |
|
| 2014-10 |
Novel irreversible EGFR tyrosine kinase inhibitor, DBPR112, as a therapeutic candidate for lung adenocarcinoma |
Cancer Research. 2014 Oct;74(19 Suppl.):Abstract No. 1756. |
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| 2014-03 |
DBPR112, a potent and selective EGFR kinase inhibitor in preclinical study |
Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 315-MEDI. |
|
| 2014-03 |
Efficient virtual screening using ligand efficiency based approach |
Abstracts of Papers - American Chemical Society. 2014 Mar;247:Article number 55-MEDI. |
|
| 2013-04-07 |
BPR000K, a novel Aurora kinase inhibitor |
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 300-MEDI. |
|
| 2013-04-07 |
3D-QSAR assisted drug design: Identification of a potent quinazoline based Aurora kinase inhibitor |
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 87-MEDI. |
|
| 2013-04-07 |
Development drug candidate targeting EGFR kinase: DBPR112 |
Abstracts of Papers - American Chemical Society. 2013 Apr 7;245:Article number 299-MEDI. |
|
| 2013-04 |
Design and synthesis of Aurora kinase inhibitors as anticancer agents |
Abstracts of Papers - American Chemical Society. 2013 Apr;245:Article number 301-MEDI. |
|
| 2012-11 |
BPR1J271, a novel FLT3 inhibitor for treating acute myeloid leukemia |
European Journal of Cancer. 2012 Nov;48(Suppl. 6):53-54. |
|
| 2012-03-25 |
Design, synthesis, and SAR studies of duel FLT-3 and Aurora kinase inhibitors |
Abstracts of Papers - American Chemical Society. 2012 Mar 25;243:Article number 48-MEDI. |
|
| 2011-09-23 |
BPR1K653, a novel Aurora Kinase Inhibitor, exhibits potent anti-proliferative activity in P-gp170 (MDR1)-mediated VX680-resistant cancer cells in vitro and in vivo |
European Journal of Cancer. 2011 Sep 23;47:S127. |
|
| 2011-09 |
Overcoming the acquired resistance to Afatinib (BIBW2992) in HCC827, a non-small cell lung cancer cell line |
European Journal of Cancer. 2011 Sep;47:S129. |
|
| 2011-09 |
Suppression of stat3 activity sensitizes gefitinib-resistant non small cell lung cancer cells |
European Journal of Cancer. 2011 Sep;47(Suppl. 1):S104. |
|
| 2011-03-27 |
Design and synthesis of potent Aurora kinase inhibitors |
Abstracts of Papers - American Chemical Society. 2011 Mar 27;241:258-MEDI. |
|
| 2011-03 |
Potent EGFR tyrosine kinase inhibitors as anticancer agents |
Abstracts of Papers - American Chemical Society. 2011 Mar;241:257-MEDI. |
|
| 2011-03 |
SAR studies of quinoline derivatives as novel anti-influenza agents |
Abstracts of Papers - American Chemical Society. 2011 Mar;241:81-MEDI. |
|
| 2010-08 |
Lead optimization of furanopyrimidine Aurora kinase inhibitors: Development of in vivo active agents in tumor xenograft models |
Abstracts of Papers - American Chemical Society. 2010 Aug;240:MEDI 332. |
|
| 2009-09 |
Fast-forwarding kinase drug discovery: aurora and EGFR kinase inhibitor lead development |
EJC Supplements. 2009 Sep;7(2):96. |
|
| 2009-03 |
Discovery and development of novel furano-pyrimidine analogs as Aurora kinase inhibitors |
Abstracts of Papers - American Chemical Society. 2009 Mar;237:MEDI 221. |
|
| 2007-07 |
Anti-influenza drug discovery |
Drugs of the Future. 2007 Jul;32(Suppl. A):97. |
|
| 2005-03 |
Promazine analogues as potential anti SARS-CoV drugs |
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U168. |
|
| 2005-03 |
Design, synthesis and sar of indole-based PPAR agonists |
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141. |
|
| 2005-03 |
Design and structure-activity relationships of novel indole-based PPAR agonists as antidiabetic agents |
Abstracts of Papers of the American Chemical Society. 2005 Mar;229(Part 2):U141. |
|
| 2004-10 |
Emergence of mutation clusters in HCV genome during continuous passage of the virus in Sip-L expressing cells |
Hepatology. 2004 Oct;40(4):255A. |
|
| 2003-09-10 |
Generation of chimeric baculovirus with histidine-tags displayed on the envelope and its purification using immobilized metal affinity chromatography |
Enzyme and Microbial Technology. 2003 Sep;33(4):445-452. |
|
| 2003-09-10 |
Combined use of GAP and AOX1 promoter to enhance the expression of human granulocyte-macrophage colony-stimulating factor in Pichia pastoris |
Enzyme and Microbial Technology. 2003 Sep;33(4):453-459. |
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