國家衛生研究院 NHRI:Item 3990099045/5523
English  |  正體中文  |  简体中文  |  全文筆數/總筆數 : 12145/12927 (94%)
造訪人次 : 926108      線上人數 : 577
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜尋範圍 查詢小技巧：
  • 您可在西文檢索詞彙前後加上"雙引號"，以獲取較精準的檢索結果
  • 若欲以作者姓名搜尋，建議至進階搜尋限定作者欄位，可獲得較完整資料
    •  進階搜尋
    主頁 ‧ 登入 ‧ 上傳 ‧ 說明 ‧ 關於NHRI ‧ 管理 到手機版


    請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/5523


    題名: Antimicrobial susceptibility of bacteremic isolates from cancer patients with or without neutropenia at a medical center in southern Taiwan
    作者: Huang, CC;Wu, CJ;Wang, LR;Lee, HC;Chang, CM;Lee, NY;Chen, TY;Ko, WC
    貢獻者: Division of Infectious Diseases
    摘要: Background: Few studies focus on comparison of antimicrobial susceptibility for bacteremic isolates in neutropenic and nonneutropenic cancer patients. The purpose of this study was to elucidate the antimicrobial susceptibility of bacteremic isolates from cancer patients. Methods: We collected bacterial isolates causing bloodstream infections in cancer patients at a tertiary care hospital from 2003 to 2005 and performed in vitro antimicrobial susceptibility of these pathogens by the disc diffusion method. Results: A total of 588 bacterial isolates were identified from 476 episodes of bloodstream infections in cancer patients. Major pathogens were Escherichia coli (22.4%), Klebsiella pneumoniae (17.6%), and Pseudomonas aeruginosa (14.1%) in neutropenic patients and E coli (13.3%), K pneumoniae (10.1%), and Staphylococcus aureus (9.7%) in nonneutropenic patients. Of S aureus, 55.8% were resistant to methicillin, and of coagulase-negative Staphylococcus 87.0%. Cefepime, cefpirome, piperacillin/tazobactam, meropenem, or imipenem in combination with or without an aminoglycoside, were active against more than 85% of gram-negative bacilli (GNB). Ceftazidime, piperacillin, or ciprofloxacin plus an aminoglycoside were also active against more than 85% of GNB. The susceptibility rate of GNB or gram-positive cocci to any agent was not different between the isolates from neutropenic and nonneutropenic patients, but more GNB isolates from the former were susceptible to imipenem or meropenem plus an aminoglycoside. Conclusion: GNB remained dominant among bacteremic isolates in cancer patients. Antimicrobial agents, especially aminoglycoside-containing combination regimens, as recommended by Infectious Diseases Society of Taiwan for febrile neutropenia, were active against more than 85% of GNB isolates.
    日期: 2011-10
    關聯: Journal of Microbiology, Immunology and Infection. 2011 Oct;44(5):376-381.
    Link to: http://dx.doi.org/10.1016/j.jmii.2011.01.035
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1684-1182&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000296662200010
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=80053620310
    顯示於類別:[吳綺容] 期刊論文

    文件中的檔案:

    檔案 描述 大小格式瀏覽次數
    SCP79951943549.pdf156KbAdobe PDF385檢視/開啟


    在NHRI中所有的資料項目都受到原著作權保護.

    TAIR相關文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回饋