國家衛生研究院 NHRI:Item 3990099045/5748
English  |  正體中文  |  简体中文  |  全文笔数/总笔数 : 12145/12927 (94%)
造访人次 : 914535      在线人数 : 1362
RC Version 6.0 © Powered By DSPACE, MIT. Enhanced by NTU Library IR team.
搜寻范围 查询小技巧：
  • 您可在西文检索词汇前后加上"双引号"，以获取较精准的检索结果
  • 若欲以作者姓名搜寻，建议至进阶搜寻限定作者字段，可获得较完整数据
    •  进阶搜寻
    主页 ‧ 登入 ‧ 上传 ‧ 说明 ‧ 关于NHRI ‧ 管理 到手机版


    jsp.display-item.identifier=請使用永久網址來引用或連結此文件: http://ir.nhri.org.tw/handle/3990099045/5748


    题名: Zinc ions induce inflammatory responses in vascular endothelial cells
    作者: Yeh, SC;Tsai, FY;Chao, HR;Tsou, TC
    贡献者: Division of Environmental Health and Occupational Medicine
    摘要: Using one particulate zinc oxide (ZnO) and two soluble zinc compounds (Zn(NO(3))(2) and Zn(CH(3)COO)(2)), we aimed to clarify if zinc ions (Zn(2+)), like particulate ZnO, caused inflammatory responses in vascular endothelial cells. Treatments of human umbilical vein endothelial cells (HUVECs) with 368.6 muM of each zinc compound caused marked increases in IkappaBalpha phosphorylation and intercellular adhesion molecule-1 (ICAM-1) expression. Treatments with Zn(CH(3)COO)(2) (50-350 muM) induced a dose-dependent ICAM-1 expression. These results show that Zn(2+) alone is sufficient to induce similar levels of ICAM-1 expression as ZnO particles, suggesting that dissolved Zn(2+) may play the major role in inflammatory effect of ZnO particles on vascular endothelial cells.
    日期: 2011-08
    關聯: Bulletin of Environmental Contamination and Toxicology. 2011 Aug;87(2):113-116.
    Link to: http://dx.doi.org/10.1007/s00128-011-0317-9
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0007-4861&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000292826900003
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79960564160
    显示于类别:[鄒粹軍] 期刊論文

    文件中的档案:

    档案 描述 大小格式浏览次数
    PUB21614444.pdf195KbAdobe PDF554检视/开启


    在NHRI中所有的数据项都受到原著作权保护.

    TAIR相关文章

    DSpace Software Copyright © 2002-2004  MIT &  Hewlett-Packard  /   Enhanced by   NTU Library IR team Copyright ©   - 回馈