國家衛生研究院 NHRI:Item 3990099045/5817
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    題名: Proton resonance frequency shift-weighted imaging for monitoring MR-guided high-intensity focused ultrasound transmissions
    作者: Chen, JW;Huang, TY;Peng, HH;Chen, WS;Tseng, WYI
    貢獻者: Division of Medical Engineering Research
    摘要: Abstract Purpose: To combine temperature-related information of phase images and magnitude images acquired from an MR spoiled gradient echo sequence using a postprocessing method referred to as PRF-shift-weighted imaging (PRFSWI). Materials and Methods: Phase images are capable of detecting shifts in proton resonance frequency (PRF) caused by local changes in temperature. Magnitude images provide anatomical information for treatment planning and positioning as well as temperature-related contrast. We used PRFSWI to produce a phase-mask and performed multiplication on the magnitude image to increase temperature-related contrast. Results: Through MRI-guided focused ultrasound (MRIgFUS) experiments (both ex vivo and in vivo), we determined that PRFSWI is capable of enhancing the contrast of a heated area even in the initial stages of transmitting high-intensity focused ultrasound energy. Conclusion: The PRFSWI images are sensitive to changes in temperature and display the heated spot directly in the magnitude images. Although the images do not provide quantitative data related to temperature, this method could be used as a complement to the phase temperature mapping method in the real-time monitoring of MRIgFUS experiments.
    日期: 2011-06
    關聯: Journal of Magnetic Resonance Imaging. 2011 Jun;33(6):1474-1481.
    Link to: http://dx.doi.org/10.1002/jmri.22582
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1053-1807&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000291267700024
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=79958274481
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