國家衛生研究院 NHRI:Item 3990099045/6176
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    Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/6176


    Title: Is the metabolic syndrome associated with cardiovascular disease, diabetes mellitus, and increased physical limitations in an elderly population if multiple chronic illnesses are taken into consideration?
    Authors: Huang, YW;Chen, CY;Weng, LJ;Wu, YC
    Contributors: Division of Geriatric Research
    Abstract: Background: The concept of metabolic syndrome (MetS) was initially designed for long-term outcome prediction in middle aged or younger individuals, but it is unclear whether MetS can be applied in older people. We explored the clinical utility of MetS for prediction of various outcomes in older people. First, we investigated whether MetS is associated with CVD and DM in the short term. Second, we took multiple chronic illnesses into consideration to examine whether MetS is associated with increased physical limitations. Methods: Participants were selected from the "Social Environment and Biomarkers of Aging Study, 2000" and the "2003 Survey of Health and Living Status of the Middle-Aged and Elderly in Taiwan" aged ≥65 years for whom complete data were available. A total of 543 older Taiwanese were included. Results: For older people who had MetS compared to those without the syndrome in 2000, the risk of CVD was 1.94 times higher in 2003 (p < 0.01) and that of DM was 3.02 times higher in 2003 (p < 0.01) after controlling for age, sex, and chronic illnesses. Hierarchical regression models of physical functions showed that MetS did not increase the explained variance in physical functional limitations. Conclusions: MetS has short-term (3 years) effects on CVD and DM. After taking chronic illnesses into consideration, no association between MetS and physical functioning was obvious. More studies are needed to clarify the relationship among MetS, chronic illnesses, and physical functioning.
    Date: 2011-09
    Relation: International Journal of Gerontology. 2011 Sep;5(3):146-149
    Link to: http://dx.doi.org/10.1016/j.ijge.2011.09.036
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1873-9598&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000299403000003
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84655164381
    Appears in Collections:[Ching-Yu Chen(2006-2010)] Periodical Articles

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