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Please use this identifier to cite or link to this item:
http://ir.nhri.org.tw/handle/3990099045/6197
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| Title: | In reply to 'Population prevalence of proteinuria and diagnostic accuracy of urine dipsticks' |
| Authors: | Wen, CP;Yang, YC;Tsai, MK;Wen, SF |
| Contributors: | Division of Health Services and Preventive Medicine |
| Abstract: | We appreciate the opportunity to clarify aspects of our editorial in response to the comments of White et al.1 In our editorial,2 the 16.9% rate of “dipstick proteinuria” referred to the result reported by White et al.3 In their study they found urine dipstick readings of “negative, trace, or ≥1+ result in 83.1%, 8%, and 8.1% of participants, respectively,” indicating that either 16.9% or 16.1% had proteinuria detected by dipstick (ie, 100% – 83.1% = 16.9% or 8% + 8.1% = 16.1%). When assessed by albumin-creatinine ratio (ACR), the proportion with proteinuria is comparable to other studies (Table 1) but prevalences given for the 2 dipstick reading categories of ≥1+ and trace or higher are substantially greater than those found in most other studies [4], [5] and [6] (8.1% vs 1%-3% and 16.1% vs 8%-9%, respectively). We have found urine dipstick protein results of trace or higher to be of value in screening for ACR ≥ 30 mg/g and were surprised by the large difference found by White et al in the proportion of participants with ACR ≥ 30 mg/g (6.6%) and those with a dipstick reading of trace or higher (16.1%). In our Taiwanese study, the prevalence of dipstick readings or trace or higher (7.9%) approximated the proportion with ACR ≥ 30 mg/g (6.9%). [3] and [4] In pooled studies by the Chronic Kidney Disease Prognosis Consortium (CKD-PC) of 1.1 million individuals,5 dipstick proteinuria ≥ 1+ was found in 3.3% (2.3% + 1.0% = 3.3%); in the Taiwan study, this value was 1.7% (0.9% + 0.8% = 1.7%; Table 1). Thus, in our opinion, the proportion with dipstick proteinuria ≥ 1+ in the study from White et al (8.1%) is higher than expected. |
| Date: | 2011-12 |
| Relation: | American Journal of Kidney Diseases. 2011 Dec;58(6):1039-1040. |
| Link to: | http://dx.doi.org/10.1053/j.ajkd.2011.10.005 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0272-6386&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:000297267500029 |
| Cited Times(Scopus): | http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=81755171279 |
| Appears in Collections: | [溫啟邦(2001-2010)] 期刊論文
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| ISI000297267500029.pdf | | 76Kb | Adobe PDF | 383 | View/Open |
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