國家衛生研究院 NHRI:Item 3990099045/6258
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    题名: Non-typhoidal Salmonella bacteraemia in elderly patients: an increased risk for endovascular infections, osteomyelitis and mortality
    作者: Chen, PL;Lee, HC;Lee, NY;Wu, CJ;Lin, SH;Shih, HI;Lee, CC;Ko, WC;Chang, CM
    贡献者: Division of Infectious Diseases
    摘要: SUMMARYNon-typhoidal Salmonella (NTS) is a common pathogen causing foodborne infections, bacteraemia, and extra-intestinal focal infections (EFIs) in humans. The study compares the clinical characteristics of elderly patients with NTS bacteraemia with those of young adults. Of 272 adults with NTS bacteraemia identified in this study, 162 (59.6%) were aged 55 years. EFIs were observed in 36% of the 162 patients. The most common EFIs in the elderly patients (55 years) was mycotic aneurysm, followed by pulmonary infections and bone/joint infections. Elderly patients more often had chronic heart, lung, renal and malignant diseases, had more EFIs, and a higher 30-day mortality rate. Independent factors of 30-day mortality in elderly patients were solid-organ tumour [adjusted odds ratio (aOR) 4.4, P=0.003], mycotic aneurysm (aOR 3.7, P=0.023) and shock (aOR 12.1, P<0.0001). HIV infection, autoimmune diseases, and receipt of immunosuppressive therapy were more often observed in young patients.
    日期: 2012-11
    關聯: Epidemiology and Infection. 2012 Nov;140(11):2037-2044.
    Link to: http://dx.doi.org/10.1017/s0950268811002901
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0950-2688&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000309724500015
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84869413530
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