國家衛生研究院 NHRI:Item 3990099045/6429
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    題名: Spheroid formation from neural stem cells on chitosan membranes
    作者: Hsu, SH;Lin, YL;Lin, TC;Tseng, TC;Lee, HT;Liao, YC;Chiu, IM
    貢獻者: Institute of Cellular and Systems Medicine
    摘要: This study demonstrates neural stem cells forming neurosphere-like three-dimensional adherent spheroids on chitosan membranes. Their state can be maintained for at least fifteen days, during which period the spheroids increase their size and number. After this period, the neural stem cells start to migrate out of the spheroids, which change in size when the culture period is prolonged. It is believed that the spheroid formation on chitosan can maintain the self-renewal and plasticity of neural stem cells for weeks, with differentiation possibly occurring at a later period. The culture of neural stem cells on certain chitosan membranes can be used to purify neural stem cells from a heterogeneous cell population.
    日期: 2012-05
    關聯: Journal of Medical and Biological Engineering. 2012 May;32(2):85-90.
    Link to: http://dx.doi.org/10.5405/jmbe.864
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1609-0985&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000303147300002
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84864022417
    顯示於類別:[邱英明] 期刊論文

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