國家衛生研究院 NHRI:Item 3990099045/6444
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    题名: Adherence patterns with first- versus second-generation antipsychotics for newly diagnosed schizophrenia in Taiwan
    作者: Chang, CM;Wu, KY;Liang, HY;Wu, ECH;Chen, CY;Wu, CS;Chen, SJ;Chang, TK;Tsai, HJ
    贡献者: Division of Mental Health and Addiction Medicine;Division of Biostatistics and Bioinformatics
    摘要: Objective: The aim of this study was to compare the early adherence patterns for first-generation antipsychotics and second-generation antipsychotics during the first month of treatment for patients newly diagnosed as having schizophrenia. Methods: With a random sample from the Taiwan national health insurance database, persons with a schizophrenia diagnosis (ICD-9-CM code 295.X) and a concurrent initial antipsychotic prescription from 1998 to 2006 were defined as being newly treated for schizophrenia. Adherence patterns within one month of diagnosis were categorized into four independent groups: refill, switch, admission, and discontinuation. Results: Treatment initiated with first-generation or second-generation antipsychotics resulted in similar rates of refill (57% versus 59%). However, patients who started with first-generation antipsychotics were significantly less likely to switch (9% versus 14%) but more likely to discontinue (34% versus 26%) medications than those whose treatment was initiated with second-generation antipsychotics. Conclusions: The data substantiated previous observations of the magnitude of adherence problems in Asian populations and highlight the importance of developing new strategies for intervention.
    日期: 2012-05
    關聯: Psychiatric Services. 2012 May;63(5):504-507.
    Link to: http://dx.doi.org/10.1176/appi.ps.201100011
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1075-2730&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000303373600022
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84860711157
    显示于类别:[陳娟瑜(2004-2010)] 期刊論文
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