國家衛生研究院 NHRI:Item 3990099045/6447

NHRI > National Institute of Environmental Health Sciences > Lukas Jyuhn-Hsiarn Lee > Periodical Articles > Item 3990099045/6447

Please use this identifier to cite or link to this item: http://ir.nhri.org.tw/handle/3990099045/6447

Title:	Estimation of benefit of prevention of occupational cancer for comparative risk assessment: Methods and examples
Authors:	Lee, LJ;Chang, YY;Liou, SH;Wang, JD
Contributors:	Division of Environmental Health and Occupational Medicine
Abstract:	ObjectivesTo quantify the life years gained and financial savings by preventing a case of occupational cancer.MethodsThe authors retrieved data from the Taiwan Cancer Registry and linked them with the National Mortality Registry to estimate the survival functions for major occupational cancers: lung, pleural mesothelioma, urinary bladder and leukaemia. Assuming a constant excess hazard for each type of cancer, the authors extrapolated lifetime survival functions by the Monte Carlo method. For each patient with cancer, the authors simulated an age- and gender-matched person without cancer based on vital statistics of Taiwan to estimate life expectancy and expected years of life lost (EYLL). By using the reimbursement data from the National Health Insurance Research Database, the authors calculated the average monthly healthcare expenditures, which were summed to estimate the lifetime healthcare expenditures after adjusting for the corresponding monthly survival probability.ResultsA total of 51 408, 136, 12 891 and 5285 new cases of lung, pleural mesothelioma, bladder and leukaemia cancers, respectively, were identified during 1997-2005 and followed until the end of 2007. The EYLL was predicted to be 13.7+/-0.1, 18.9+/-0.7, 4.7+/-0.3 and 19.4+/-0.5 years for these cancers, respectively, and the lifetime healthcare expenditures with a 3% annual discount were predicted to be US$22 359, US$14 900, US$51 987 and US$59 741, respectively.ConclusionsThe burden of these occupational cancers, in terms of EYLL and lifetime healthcare expenditures, was substantial. Such estimates may provide useful empirical evidence for comparative risk assessment that can be applied in health policy-making and clinical decision-making.
Date:	2012-08
Relation:	Occupational and Environmental Medicine. 2012 Aug;69(8):582-586.
Link to:	http://dx.doi.org/10.1136/oemed-2011-100462
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=1351-0711&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000306375400009
Cited Times(Scopus):	http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84864098504
Appears in Collections:	[Lukas Jyuhn-Hsiarn Lee] Periodical Articles [Saou-Hsing Liou] Periodical Articles

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