國家衛生研究院 NHRI:Item 3990099045/6576
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    题名: Murine typhus in southern Taiwan during 1992-2009
    作者: Chang, K;Chen, YH;Lee, NY;Lee, HC;Lin, CY;Tsai, JJ;Lu, PL;Chen, TC;Hsieh, HC;Lin, WR;Lai, PC;Chang, CM;Wu, CJ;Lai, CH;Ko, WC
    贡献者: Division of Infectious Diseases
    摘要: Abstract. Clinical information regarding murine typhus in Taiwan is limited. In this study, 81 cases of serologically documented murine typhus during 1992-2009 at four referral hospitals in southern Taiwan were analyzed. There was a significant correlation between average environmental temperature and case numbers of murine typhus (r = 0.747, P = 0.005). Acute hepatitis was found in 67% of cases, and hyperbilirubinemia (serum total bilirubin >/= 23.9 mumol/L) was found in 38%. The intervals between the initiation of appropriate therapy to defervescence were longer in patients with hyperbilirubinemia than those without hyperbilirubinemia (6.1 versus 4.1 days; P = 0.015). Nine (11.1%) showed development of severe illnesses such as acute respiratory distress syndrome (2 patients), aseptic meningitis (3), and acute renal failure (4). Only one died of acute respiratory distress syndrome. Cases of murine typhus were often found during the summer and had acute febrile hepatitis. Those patients with hyperbilirubinemia tended to have a delayed recovery even with appropriate therapy.
    日期: 2012-07
    關聯: American Journal of Tropical Medicine and Hygiene. 2012 Jul;87(1):141-147.
    Link to: http://dx.doi.org/10.4269/ajtmh.2012.11-0465
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0002-9637&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000306153500024
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84863733538
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