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Endosomes serve as signaling platfo...
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2024-11-08
Endosomes serve as signaling platforms for RIG-I ubiquitination and activation
Science Advances. 2024 Nov 08;10(45):Article number eadq0660.
2024-06-14
DUSP22 inhibits lung tumorigenesis by suppression of EGFR/c-Met signaling
Cell Death Discovery. 2024 Jun 14;10:Article number 285.
2024-06
UHRF1P contributes to IL-17A-mediated systemic lupus erythematosus via UHRF1-MAP4K3 axis
Journal of Autoimmunity. 2024 Jun;146:Article number 103221.
2024-03-27
Association of TRAIL receptor with phosphatase SHP-1 enables repressing T cell receptor signaling and T cell activation through inactivating Lck
Journal of Biomedical Science. 2024 Mar 27;31:Article number 33.
2024-01-15
The phosphatase DUSP22 inhibits UBR2-mediated K63-ubiquitination and activation of Lck downstream of TCR signalling
Nature Communications. 2024 Jan 15;15:Article number 532.
2023-12-05
Dual-specificity phosphatase 6 deficiency attenuates arterial-injury-induced intimal hyperplasia in mice
International Journal of Molecular Sciences. 2023 Dec 05;24(24):Article number 17136.
2023-11-01
DUSP8 induces TGF-beta–stimulated IL-9 transcription and Th9-mediated allergic inflammation by promoting nuclear export of Pur-Alpha
Journal of Clinical Investigation. 2023 Nov 01;133(21):Article number e166269.
2023-08-22
ACE2 in chronic disease and COVID-19: Gene regulation and post-translational modification
Journal of Biomedical Science. 2023 Aug 22;30:Article number 71.
2023-06
Hematopoietic progenitor kinase 1 inhibits the development and progression of pancreatic intraepithelial neoplasia
Journal of Clinical Investigation. 2023 Jun 15;133(12):Article number e163873.
2023-05-01
DUSP8 induces TGF-Beta-stimulated IL-9 transcription and Th9-mediated immune responses by inactivating a transcriptional repressor
Journal of Immunology. 2023 May 01;210(Suppl. 1):Abstract number 243.04.
2023-04-22
DUSP6 deficiency attenuates neurodegeneration after global cerebral ischemia
International Journal of Molecular Sciences. 2023 Apr 22;24(9):Article number 7690.
2023-02-10
Dual-specificity phosphatases 22-deficient T cells contribute to the pathogenesis of ankylosing spondylitis
BMC Medicine. 2023 Feb 10;21:Article number 46.
2022-07-27
SARS-CoV-2 spike protein enhances MAP4K3/GLK-induced ACE2 stability in COVID-19
EMBO Molecular Medicine. 2022 Jul 27:Article number e15904.
2022-07-18
MAP4K3/GLK inhibits Treg differentiation by direct phosphorylating IKK beta and inducing IKK beta-mediated FoxO1 nuclear export and Foxp3 downregulation
Theranostics. 2022 Jul 18;12(12):5744-5760.
2022-06-15
DUSP3 regulates phosphorylation-mediated degradation of occludin and is required for maintaining epithelial tight junction
Journal of Biomedical Science. 2022 Jun 15;29:Article number 40.
2022-02-18
Single-cell RNA sequencing uncovers the individual alteration of intestinal mucosal immunocytes in Dusp6 knockout mice
iScience. 2022 Feb 18;25(2):Article number 103738.
2022-02
Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus
Annals of the Rheumatic Diseases. 2022 Feb;81(2):243-254.
2022-01
Induction of interferon-gamma and tissue inflammation by overexpression of eosinophil cationic protein in T cells and exosomes
Arthritis and Rheumatology. 2022 Jan;74(1):92-104.
2021-11-23
Identification of a gut microbiota member that ameliorates DSS-induced colitis in intestinal barrier enhanced Dusp6-deficient mice
Cell Reports. 2021 Nov 23;37(8):Article number 110016.
2021-10-25
BPI overexpression suppresses Treg differentiation and induces exosome-mediated inflammation in systemic lupus erythematosus
Theranostics. 2021 Oct 25;11(20):9953-9966.
2020-10-12
Structural insights into the active site formation of dusp22 in n-loop-containing protein tyrosine phosphatases
International Journal of Molecular Sciences. 2020 Oct 12;21(20):Article number 7515.
2020-08-12
DUSP11 attenuates lipopolysaccharide-induced macrophage activation by targeting TAK1
Journal of Immunology. 2020 Aug 12;205(6):1644-1652.
2019-12
DUSP22 suppresses prostate cancer proliferation by targeting the EGFR-AR axis
FASEB Journal. 2019 Dec 5;33(12):14653-14667.
2019-11-13
MAP4K family kinases and DUSP family phosphatases in T-Cell signaling and systemic lupus erythematosus
Cells. 2019 Nov 13;8(11):Article number 1433.
2019-10-22
MAP4K3/GLK in autoimmune disease, cancer and aging
Journal of Biomedical Science. 2019 Oct 22;26:Article number 82.
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