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Endosomes serve as signaling platfo...
DUSP22 inhibits lung tumorigenesis ...
UHRF1P contributes to IL-17A-mediat...
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The phosphatase DUSP22 inhibits UBR...
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题名
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2016-07
Prediction of early hepatocellular carcinoma recurrence using germinal center kinase-like kinase
Oncotarget. 2016 Jul;7(31):49765-49776.
2016-05
A multi-prong global study provides insights to gut microbiota and mucosal immunity in dusp6-deficiency conferred obesity-resistance
Journal of Immunology. 2016 May;196(1 Suppl.):Meeting Abstract 67.15.
2016-05
Roles of innate immune regulator TAPE in RIG-I signaling and antiviral defenses
Journal of Immunology. 2016 May;196(1 Suppl.) :Abstract number 203.13.
2016-05
Emerging roles of an innate immune regulator TAPE in Toll-like receptors, RIG-I-like receptors, and beyond
Journal of Immunology. 2016 May;196(1 Suppl.):Meeting Abstract 202.35.
2016-03-08
Epigenetic regulation of HGK/MAP4K4 in T cells of type 2 diabetes patients
Oncotarget. 2016 Mar 8;7(10):10976-10989.
2016-01
MAP4K family kinases in immunity and inflammation
Advances in Immunology. 2016 Jan;129:277-314.
2016-01
TRAF2-mediated Lys63-linked ubiquitination of DUSP14/MKP6 is essential for its phosphatase activity
Cellular Signalling. 2016 Jan;28(1):145-151.
2014-09-30
Map kinase kinase kinase kinase 3 (MAP4K3) as a biomarker and therapeutic target for autoimmune disease, cancer, inflammation and IL-17-associated disease
US8846311/2014-09-30
2014-09-12
PP4 is essential for germinal center formation and class switch recombination in mice
PLoS ONE. 2014 Sep 12;9(9):Article number e107505.
2014-08-06
HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance
Nature Communications. 2014 Aug 6;5:Article number 4602.
2014-05-07
Protein phosphatase 4 is an essential positive regulator for Treg development, function, and protective gut immunity
Cell and Bioscience. 2014 May 7;4:Article number 25.
2014-04-09
The phosphatase JKAP/DUSP22 inhibits T-cell receptor signalling and autoimmunity by inactivating Lck
Nature Communications. 2014 Apr 9;5:Article number 3618.
2014-02-15
Dual-specificity Phosphatase 14 (DUSP14/MKP6) negatively regulates TCR signaling by inhibiting TAB1 activation
Journal of Immunology. 2014 Feb 15;192(4):1547-1557.
2014-02
The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1
Journal of Biological Chemistry. 2014 Feb 14;289(7):4009-4017.
2013-10
Germinal center kinase-like kinase overexpression in T cells as a novel biomarker in rheumatoid arthritis
Arthritis and Rheumatism. 2013 Oct;65(10):2573-2582.
2013-07
The serine/threonine phosphatase PP4 is required for pro-B cell development through its promotion of immunoglobulin VDJ recombination
PLoS ONE. 2013 Jul;8(7):Article number e68804.
2012-10-05
Attenuation of T cell receptor signaling by serine phosphorylation-mediated lysine 30 ubiquitination of SLP-76 protein
Journal of Biological Chemistry. 2012 Oct 5;287(41):34091-34100.
2012-09-14
TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity
Journal of Biological Chemistry. 2012 Sep 14;287(38):32216-32221.
2012-08-06
Germinal center kinase-like kinase (GLK/MAP4K3) expression is increased in adult-onset Still's disease and may act as an activity marker
BMC Medicine. 2012 Aug 6;10(1):Article number 84.
2012-07
DUSPs, to MAP kinases and beyond
Cell and Bioscience. 2012 Jul;2(1):Article number24.
2012-07
Regulation of PKC-theta function by phosphorylation in T cell receptor signaling
Frontiers in Immunology. 2012 Jul;3:Article number 197.
2012-05
Defective regulatory T cells function and spontaneous colitis induced by protein phosphatase 4-deficiency
Journal of Immunology. 2012 May;188(Suppl):120.14.
2012-03
Down-regulation of B-cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and Ubiquitination of the activated B cell linker protein (BLNK)
Journal of Biological Chemistry. 2012 Mar;287(14):11037-11048.
2012-02
DUSP4 deficiency enhances CD25 expression and CD4(+) T-cell proliferation without impeding T-cell development
European Journal of Immunology. 2012 Feb;42(2):476-488.
2011-10
The kinase GLK controls autoimmunity and NF-kappa B signaling by activating the kinase PKC-theta in T cells
Nature Immunology. 2011 Oct;12(11):1113-1118.
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