國家衛生研究院 NHRI:Item 3990099045/6737
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    题名: X-ray imaging of tumor growth in live mice by detecting gold-nanoparticle-loaded cells
    作者: Chien, CC;Chen, HH;Lai, SF;Hwu, Y;Petibois, C;Yang, CS;Chu, Y;Margaritondo, G
    贡献者: Center for Nanomedicine Research
    摘要: We show that sufficient concentrations of gold nanoparticles produced by an original synthesis method in EMT-6 and CT-26 cancer cells make it possible to detect the presence, necrosis and proliferation of such cells after inoculation in live mice. We first demonstrated that the nanoparticles do not interfere with the proliferation process. Then, we observed significant differences in the tumor evolution and the angiogenesis process after shallow and deep inoculation. A direct comparison with pathology optical images illustrates the effectiveness of this approach.
    日期: 2012-08-29
    關聯: Scientific Reports. 2012 Aug 29;2:Article number 610.
    Link to: http://dx.doi.org/10.1038/srep00610
    JIF/Ranking 2023: http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=2045-2322&DestApp=IC2JCR
    Cited Times(WOS): https://www.webofscience.com/wos/woscc/full-record/WOS:000308141100004
    Cited Times(Scopus): http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=84866134937
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