Primary squamous cell carcinoma (SCC) of the thyroid is rare, constituting less than 1% of all primary thyroid carcinomas.1,2 It is an aggressive disease with a poor prognosis and is usually composed of tumor cells that exhibit complete squamous differentiation.3 Investigations should be performed to exclude metastasis from another SCC tumor or involvement of the thyroid from an adjacent SCC.3 The typical initial presentation begins with a rapidly enlarging neck mass followed by tracheal and esophageal compression and respiratory compromise. Cardiac metastases from thyroid cancer are quite uncommon and potentially fatal. Here we describe a patient with primary SCC of the thyroid with cardiac metastases and right ventricle outflow tract (RVOT) obstruction.
Date:
2012-09-10
Relation:
Journal of Clinical Oncology. 2012 Sep 10;30(26):E260-E263.