 |
English
|
正體中文
|
简体中文
|
Items with full text/Total items : 12340/13424 (92%)
Visitors : 2000118
Online Users : 178
|
|
|
Loading...
|
Please use this identifier to cite or link to this item:
http://ir.nhri.org.tw/handle/3990099045/6855
|
| Title: | Which subtypes of cardiorenal syndrome is associated with worse clinical outcomes? |
| Authors: | Sung, SH;Hsu, PF;Cheng, HM;Yeh, JS;Liu, WL;Chuang, SY |
| Contributors: | Division of Health Services and Preventive Medicine |
| Abstract: | Background: The cardiorenal syndrome (CRS) indicated intimately interplays between dysfunctional heart and kidney, among which primary disorderof one organ often results in secondary damage to the other. Although therehave been classifications of five, proposed to discriminate the complexity of this cluster of conditions, whether their clinical impacts on cardiovascular morbidities and mortalities are different or not remain to be elucidated. Methods: A nationwide population-based study using the Taiwan National Health Insurance database was conducted fromthe 1 million sampling cohort data set. A total of 2838 patients who presented with both heart failure (HF) and chronic kidney disease(CKD) during 1997 to 2009 were identified. The control group consisted of 28380 subjects by matching age and sex. Results: Among 2838 subjects withCRS, 1203 patients presented withHF ahead of CKD (group 1), 1351presented with initial CKD (group 2), and 284 subjects had concurrent HF and CKD within 1month (group 3). The group 3 was younger, more likely to be women,and had less diabetes. During a median follow-up duration of 2.84 years, patients with CRS had higher adverse events for coronary heart disease (CHD) (97.7 vs. 8.5/1000 person-year), stroke (45.8 vs. 18.3), and death (55.1 vs. 9.1) comparing to the control group. Among 2838 subjects with CRS, group 3 had the lowest event rate for stroke, CHD, and death comparing to the other groups (Figure 1). Such the survival advantage remained true inmultivariate analyses when age and comorbidities were accounted for. Conclusions: The CRS indeed carried high risks for cardiovascular morbidity and mortality. However, a leading chronicity of HF or CKD rather than an acute insult to both organs is associated with worseclinical outcomes. |
| Date: | 2012-08 |
| Relation: | European Heart Journal. 2012 Aug;33(Suppl. 1):331. |
| Link to: | http://dx.doi.org/10.1093/eurheartj/ehs281 |
| JIF/Ranking 2023: | http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0195-668X&DestApp=IC2JCR |
| Cited Times(WOS): | https://www.webofscience.com/wos/woscc/full-record/WOS:000308012402557 |
| Appears in Collections: | [莊紹源] 會議論文/會議摘要
|
Files in This Item:
| File |
Description |
Size | Format | |
|---|
| ISI000308012402557.pdf | | 134Kb | Adobe PDF | 550 | View/Open |
|
All items in NHRI are protected by copyright, with all rights reserved.
|
