國家衛生研究院 NHRI:Item 3990099045/6961

NHRI > National Institute of Environmental Health Sciences > Shu-Li Wang > Conference Papers/Meeting Abstract > Item 3990099045/6961

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Title:	Relationships between concentrations of arachidonic and docosahexaenoic acids in cord blood and placental polychlorinated dibenzo-p-dioxins (PCDD), dibenzofurans (PCDF), and polychlorinated biphenyls (PCB) at delivery
Authors:	Su, YT;Sun, PY;Wang, SL;Huang, MC
Contributors:	Division of Environmental Health and Occupational Medicine
Abstract:	Long chain polyunsaturated fatty acids (LCPUFA), ARA and DHA have positive effects, and environmental toxins, polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/F) and polychlorinated biphenyls (PCB) have negative effects on perinatal development. Previous studies showed that placental toxic equivalent (TEQ) levels of PCDD/F and PCB correlated significantly with those of maternal blood, human milk, and cord blood in Taiwanese women, thus placental levels are considered indicators as perinatal accumulative exposure of dioxin and PCB (Chemosphere 54 (2004) 1459–1473). This study aimed to investigate correlations between cord blood concentrations of ARA/DHA with placental TEQ of PCDD/F and PCB in 31 pregnant women from Taiwan. Concentrations of ARA(wt%) in cord blood did not associate with placental TEQ of PCDD/F and indicator/dioxin-like PCB(p=0.602–0.735). Cord blood DHA(wt%) also did not show correlations with PCDD (p=0.097), PCDF (p=0.219), indicator PCB (p=0.108) or dioxin-like PCB (p=0.055). Future study will be directed to investigate relationships among food consumption and LCPUFA/dioxin/PCB levels in various peinatal biospecimens in a more representative sample size.
Date:	2012-04
Relation:	FASEB Journal. 2012 Apr;26:1014.3.
Link to:	http://www.fasebj.org/cgi/content/meeting_abstract/26/1_MeetingAbstracts/1014.3
JIF/Ranking 2023:	http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=NHRI&SrcApp=NHRI_IR&KeyISSN=0892-6638&DestApp=IC2JCR
Cited Times(WOS):	https://www.webofscience.com/wos/woscc/full-record/WOS:000310711302341
Appears in Collections:	[Shu-Li Wang] Conference Papers/Meeting Abstract

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